# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4269174 | B | Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by substrate addition and measured after 15 to 20 mins by spectrophotometric method | Homo sapiens | 17 | ALA4265982 | assay format | Scientific Literature | |
2. | ALA4269175 | B | Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by substrate addition and measured after 15 to 20 mins by spectrophotometric method | Homo sapiens | 17 | ALA4265982 | assay format | Scientific Literature | |
3. | ALA4269176 | B | Selectivity index, ratio of IC50 for human TNAP expressed in African green monkey COS7 cell membranes to IC50 for human IAP expressed in African green monkey COS7 cell membranes | Homo sapiens | 17 | ALA4265982 | assay format | Scientific Literature | |
4. | ALA4269177 | F | Cytotoxicity against human HeLa cells assessed as cell growth inhibition at 100 uM after 24 hrs by MTT assay | Homo sapiens | 15 | ALA4265982 | cell-based format | Scientific Literature | |
5. | ALA4269178 | B | Competitive inhibition of human TNAP expressed in African green monkey COS7 cell membranes up to 1.5 uM using CDP-star as substrate pretreated for 5 to 10 mins followed by substrate addition and measured after 15 to 20 mins by double reciprocal plot analysis | Homo sapiens | 1 | ALA4265982 | assay format | Scientific Literature |