# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4270045 | B | Inhibition of KDM4A (1 to 350 residues) (unknown origin) using H3 ( 1 to 15 residues) K9me3 as substrate preincubated for 15 min followed by substrate addition measured after 15 mins by FDH-coupled demethylase assay | Homo sapiens | 3 | ALA4266040 | single protein format | Scientific Literature | |
2. | ALA4270046 | B | Inhibition of KDM5A ARID/PhD1 domain deletion mutant (1 to 739 residues) (unknown origin) using H3 ( 1 to 24 residues) K4me3 as substrate preincubated for 15 min followed by substrate addition measured after 15 mins by FDH-coupled demethylase assay | Homo sapiens | 3 | ALA4266040 | single protein format | Scientific Literature | |
3. | ALA4270047 | B | Inhibition of KDM6A (880 to 1401 residues) (unknown origin) using H3 ( 21 to 44 residues) K27me3 as substrate preincubated for 15 min followed by substrate addition measured after 15 mins by FDH-coupled demethylase assay | Homo sapiens | 3 | ALA4266040 | single protein format | Scientific Literature | |
4. | ALA4270048 | B | Binding affinity to KDM5A ARID/PhD1 domain deletion mutant (1 to 588 residues) (unknown origin) by ITC assay | Homo sapiens | 5 | ALA4266040 | single protein format | Scientific Literature | |
5. | ALA4270085 | B | Selectivity ratio of IC50 for KDM4A (1 to 350 residues) (unknown origin) to IC50 for KDM5A ARID/PhD1 domain deletion mutant (1 to 739 residues) (unknown origin) | Homo sapiens | 3 | ALA4266040 | assay format | Scientific Literature | |
6. | ALA4270086 | B | Selectivity ratio of IC50 for KDM5A ARID/PhD1 domain deletion mutant (1 to 739 residues) (unknown origin) to IC50 for KDM6A (880 to 1401 residues) (unknown origin) | Homo sapiens | 3 | ALA4266040 | assay format | Scientific Literature |