# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4257413 | F | Agonist activity at human GLP2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP accumulation by AlphaScreen assay | Homo sapiens | 15 | cell-based format | Patent Bioactivity Data | ||
2. | ALA4257414 | F | Agonist activity at human GLP1 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP accumulation by AlphaScreen assay | Homo sapiens | 14 | cell-based format | Patent Bioactivity Data | ||
3. | ALA4257416 | F | In vivo agonist activity at GLP2R in Wistar rat assessed as increase in small intestinal wet weight administered sc once daily for 4 days measured on day 5 | Rattus norvegicus | 1 | organism-based format | Patent Bioactivity Data | ||
4. | ALA4257417 | F | In vivo agonist activity at GLP2R in diet-induced obese C57BL/6J mouse assessed as increase in small intestinal wet weight at 250 to 500 nmol/kg, sc bid for 14 days | Mus musculus | 1 | organism-based format | Patent Bioactivity Data | ||
5. | ALA4257418 | F | In vivo agonist activity at GLP2R in diet-induced obese C57BL/6J mouse assessed as increase in large intestinal wet weight at 250 to 500 nmol/kg, sc bid for 14 days | Mus musculus | 1 | organism-based format | Patent Bioactivity Data | ||
6. | ALA4257419 | F | Antidiabetic activity in diet-induced obese C57BL/6J mouse assessed as decrease in fasting blood glucose level at 250 to 500 nmol/kg, sc bid for 14 days fasted overnight on day 11 to 12 and measured on day 14 | Mus musculus | 1 | organism-based format | Patent Bioactivity Data | ||
7. | ALA4257420 | F | Antidiabetic activity in diet-induced obese C57BL/6J mouse assessed as decrease in plasma insulin level at 250 to 500 nmol/kg, sc bid for 14 days fasted overnight on day 11 to 12 and measured on day 14 | Mus musculus | 1 | organism-based format | Patent Bioactivity Data | ||
8. | ALA4257421 | F | Antidiabetic activity in diet-induced obese C57BL/6J mouse assessed as decrease in insulin resistance by measuring lower HOMA-IR index at 250 to 500 nmol/kg, sc bid for 14 days fasted overnight on day 11 to 12 and measured on day 14 | Mus musculus | 1 | organism-based format | Patent Bioactivity Data |