# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4257019 | B | Binding affinity to N-terminal GST tagged CNK PH domain (unknown origin) by SPR spectroscopy | Homo sapiens | 21 | assay format | Patent Bioactivity Data | ||
2. | ALA4257022 | B | Competitive inhibition of CNK1 (unknown origin) binding to PIP3 (unknown origin) at 50 uM by SPR spectroscopy | Homo sapiens | 19 | assay format | Patent Bioactivity Data | ||
3. | ALA4257027 | F | Growth inhibition of human NCI-H1993 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
4. | ALA4257028 | F | Growth inhibition of human A549 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4257029 | F | Growth inhibition of human NCI-H157 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
6. | ALA4257030 | F | Growth inhibition of human HCC515 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
7. | ALA4257031 | F | Growth inhibition of human NCI-H1944 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
8. | ALA4257032 | F | Growth inhibition of human NCI-H1373 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
9. | ALA4257033 | F | Growth inhibition of human HCC44 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
10. | ALA4257034 | F | Growth inhibition of human NCI-H1792 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
11. | ALA4257035 | F | Growth inhibition of human NCI-H23 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
12. | ALA4257036 | F | Growth inhibition of human NCI-H2122 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
13. | ALA4257037 | F | Antiproliferative activity against human NSCLC cells expressing mutant KRAS assessed as inhibition of 2D cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 15 | cell-based format | Patent Bioactivity Data | ||
14. | ALA4257038 | F | Antiproliferative activity against human NSCLC cells expressing mutant KRAS assessed as inhibition of 3D cell growth after 3 days | Homo sapiens | 6 | cell-based format | Patent Bioactivity Data | ||
15. | ALA4257051 | B | Inhibition of CNKSR1 in human NCI-H1573 cells expressing mutant KRAS assessed as reduction in ERK phosphorylation at 3 to 30 uM incubated for 24 hrs | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
16. | ALA4257052 | B | Inhibition of CNKSR1 in human NCI-H1573 cells expressing mutant KRAS assessed as reduction in EGFR phosphorylation at 3 to 10 uM incubated for 24 hrs | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
17. | ALA4257053 | B | Inhibition of CNKSR1 in human NCI-H1573 cells expressing mutant KRAS assessed as reduction in EGFR phosphorylation at 30 uM incubated for 24 hrs | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
18. | ALA4257054 | F | Growth inhibition of human NCI-H1573 cells expressing wild type KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 7 | cell-based format | Patent Bioactivity Data | ||
19. | ALA4257055 | B | Competitive inhibition of CNK1 (unknown origin) binding to PIP3 (unknown origin) by SPR spectroscopy | Homo sapiens | 3 | assay format | Patent Bioactivity Data | ||
20. | ALA4419273 | F | Growth inhibition of human NCI-H1975 cells incubated for 3 days | Homo sapiens | 35 | cell-based format | Patent Bioactivity Data |