| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4264872 | B | Inhibition of Mycobacterium tuberculosis H37Rv FadD32 assessed as reduction in bacterial viability after 6 days by resazurin dye based fluorescence assay | Mycobacterium tuberculosis H37Rv | 32 | single protein format | Scientific Literature | ||
| 2. | ALA4264873 | P | Kinetic solubility of the compound at pH 7.4 by chemiluminescence nitrogen detection method | 29 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA4264874 | A | Protein binding in mouse plasma a 5 uM after 5 hrs by UPLC-MS based rapid equilibrium dialysis method | Mus musculus | 1 | cell-free format | Scientific Literature | ||
| 4. | ALA4264875 | A | Protein binding in human plasma a 5 uM after 5 hrs by UPLC-MS based rapid equilibrium dialysis method | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 5. | ALA4264876 | A | Metabolic stability in mouse liver microsomes at 1 uM after 60 mins by UPLC-MS/MS analysis | Mus musculus | 4 | microsome format | Scientific Literature | ||
| 6. | ALA4264877 | A | Metabolic stability in human liver microsomes at 1 uM after 60 mins by UPLC-MS/MS analysis | Homo sapiens | 4 | microsome format | Scientific Literature | ||
| 7. | ALA4264880 | A | Plasma clearance in mouse at 1 mg/kg, iv | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA4264881 | F | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv harboring FadD32 mutant after 6 days by resazurin dye based fluorescence assay | Mycobacterium tuberculosis | 4 | organism-based format | Scientific Literature |
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