# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4263518 | B | Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells using DHO as substrate measured after 60 secs | Leishmania major | 56 | ALA4261582 | cell-based format | Scientific Literature | |
2. | ALA4263519 | B | Binding affinity to Leishmania major DHODH assessed as change in melting temperature at 100 uM by differential scanning fluorimetry-based ThermoFMN assay | Leishmania major | 12 | ALA4261582 | single protein format | Scientific Literature | |
3. | ALA4263520 | B | Binding affinity to Leishmania major DHODH assessed as change in melting temperature at 500 uM by differential scanning fluorimetry-based ThermoFMN assay | Leishmania major | 12 | ALA4261582 | single protein format | Scientific Literature | |
4. | ALA4263521 | B | Binding affinity to Leishmania major DHODH assessed as change in melting temperature at 1000 uM by differential scanning fluorimetry-based ThermoFMN assay | Leishmania major | 12 | ALA4261582 | single protein format | Scientific Literature | |
5. | ALA4263522 | B | Binding affinity to Leishmania major DHODH assessed as change in melting temperature at 100 uM by SYPRO orange dye-based differential scanning fluorimetry | Leishmania major | 12 | ALA4261582 | single protein format | Scientific Literature | |
6. | ALA4263523 | B | Binding affinity to Leishmania major DHODH assessed as change in melting temperature at 500 uM by SYPRO orange dye-based differential scanning fluorimetry | Leishmania major | 12 | ALA4261582 | single protein format | Scientific Literature | |
7. | ALA4263524 | B | Binding affinity to Leishmania major DHODH assessed as change in melting temperature at 1000 uM by SYPRO orange dye-based differential scanning fluorimetry | Leishmania major | 12 | ALA4261582 | single protein format | Scientific Literature | |
8. | ALA4263534 | F | Antitrypanosomal activity against Trypanosoma cruzi epimastigotes after 72 hrs | Trypanosoma cruzi | 2 | ALA4261582 | organism-based format | Scientific Literature | |
9. | ALA4263535 | F | Antitrypanosomal activity against Trypanosoma cruzi trypomastigote after 72 hrs | Trypanosoma cruzi | 1 | ALA4261582 | organism-based format | Scientific Literature | |
10. | ALA4263536 | F | Antitrypanosomal activity against Trypanosoma cruzi amastigotes after 72 hrs | Trypanosoma cruzi | 1 | ALA4261582 | organism-based format | Scientific Literature |