# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4269803 | B | Inhibition of human CE1 using o-NPA as substrate | Homo sapiens | 4 | single protein format | Scientific Literature | ||
2. | ALA4269804 | B | Inhibition of human intestinal carboxylesterase using o-nitrophenyl acetate as substrate | Homo sapiens | 4 | assay format | Scientific Literature | ||
3. | ALA4269805 | B | Inhibition of human AChE using acetylthiocholine as substrate | Homo sapiens | 4 | single protein format | Scientific Literature | ||
4. | ALA4269806 | B | Inhibition of human BuChE using butyrylhiocholine as substrate | Homo sapiens | 4 | single protein format | Scientific Literature | ||
5. | ALA4269807 | B | Irreversible inhibition of human CE1 assessed as residual activity preincubated with enzyme followed by compound dilution measured after 18 hrs using o-NPA as substrate relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
6. | ALA4269808 | B | Irreversible inhibition of human intestinal carboxylesterase assessed as residual activity preincubated with enzyme followed by compound dilution measured after 18 hrs using o-NPA as substrate relative to control | Homo sapiens | 5 | assay format | Scientific Literature | ||
7. | ALA4269809 | B | Binding affinity to serine residue of human CE1 assessed as adduct formation at 10 uM by mass spectrum analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
8. | ALA4269811 | B | Inhibition of human CE1 expressed in human U373MG cells assessed as reduction in enzyme-mediated oseltamivir hydrolysis at 10 uM preincubated for 10 mins followed by oseltamivir addition measured after 30 mins by UPLC-MS analysis relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
9. | ALA4269812 | B | Inhibition of human CE1 expressed in human U373MG cells assessed as reduction in enzyme-mediated oseltamivir hydrolysis by measuring oseltamivir carboxylate level at 10 uM preincubated for 10 mins followed by oseltamivir addition measured after 30 mins by UPLC-MS analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
10. | ALA4269813 | B | Inhibition of human AChE at 10 uM using acetylthiocholine as substrate relative to control | Homo sapiens | 4 | single protein format | Scientific Literature | ||
11. | ALA4269814 | B | Inhibition of human BuChE at 10 uM using butyrylhiocholine as substrate relative to control | Homo sapiens | 4 | single protein format | Scientific Literature |