# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4254597 | B | Induction of BubR1 hyperphosphorylation in human HeLa cells by Western blot analysis | Homo sapiens | 2 | ALA4251633 | cell-based format | Scientific Literature | |
2. | ALA4254598 | F | Anticlonogenic activity against human MDA-MB-231 cells incubated for 48 hrs followed by replacement with fresh medium measured after 7 to 10 days by gentian violet staining based assay | Homo sapiens | 2 | ALA4251633 | cell-based format | Scientific Literature | |
3. | ALA4254599 | F | Antiproliferative activity against human A2780 cells after 48 hrs by MTT assay | Homo sapiens | 51 | ALA4251633 | cell-based format | Scientific Literature | |
4. | ALA4254600 | F | Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay | Homo sapiens | 51 | ALA4251633 | cell-based format | Scientific Literature | |
5. | ALA4254601 | F | Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay | Homo sapiens | 51 | ALA4251633 | cell-based format | Scientific Literature | |
6. | ALA4254602 | F | Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay | Homo sapiens | 51 | ALA4251633 | cell-based format | Scientific Literature | |
7. | ALA4254603 | A | Growth inhibition of HOSEC at 1 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 2 | ALA4251633 | assay format | Scientific Literature | |
8. | ALA4254604 | B | Inhibition of pig brain tubulin polymerization measured every 1 min for 20 mins by spectrophotometric method | Sus scrofa | 4 | ALA4251633 | assay format | Scientific Literature | |
9. | ALA4254605 | B | Inhibition of alpha-tubulin polymerization in human HeLa cells assessed as increase in ratio of supernatant faction to pellet fraction at 500 nM after 6 hrs by Western blot analysis | Homo sapiens | 4 | ALA4251633 | cell-based format | Scientific Literature | |
10. | ALA4254606 | B | Disruption of microtubule structure in human SKOV3 cells assessed as decrease in density at 100 nM after 24 hrs by DAPI staining based immunofluorescence assay | Homo sapiens | 2 | ALA4251633 | cell-based format | Scientific Literature | |
11. | ALA4254608 | F | Antiangiogenic activity against HUVEC assessed as disruption of capillary-like tube formation at 50 nM after 12 hrs by inverted microscopic method | Homo sapiens | 1 | ALA4251633 | cell-based format | Scientific Literature | |
12. | ALA4254610 | F | Anti-vascular activity in Balb/c nude mouse assessed as inhibition of VEGF-induced capillary blood vessel formation using sc injected matrigel plug supplemented with 100 nM test compound mixed with VEGF and measured after 1 week by matrigel plug assay | Mus musculus | 2 | ALA4251633 | organism-based format | Scientific Literature | |
13. | ALA4254611 | F | Anti-vascular activity in Balb/c nude mouse assessed as inhibition of VEGF-induced capillary blood vessel formation by measuring reduction in hemoglobin level using sc injected matrigel plug supplemented with 100 nM test compound mixed with VEGF and measured after 1 week by matrigel plug assay | Mus musculus | 2 | ALA4251633 | organism-based format | Scientific Literature | |
14. | ALA4254612 | F | Cell cycle arrest in human HeLa cells assessed as accumulation at G2/M-phase at 25 to 50 nM after 24 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4251633 | cell-based format | Scientific Literature | |
15. | ALA4254614 | F | Cell cycle arrest in human HeLa cells assessed as accumulation at G2/M-phase at 50 nM after 24 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 2 | ALA4251633 | cell-based format | Scientific Literature | |
16. | ALA4254615 | F | Upregulation of Cyclin-B1 protein expression in human HeLa cells at 50 to 200 nM by Western blot analysis | Homo sapiens | 2 | ALA4251633 | cell-based format | Scientific Literature | |
17. | ALA4254616 | B | Induction of histone-H3 phosphorylation in human HeLa cells by Western blot analysis | Homo sapiens | 2 | ALA4251633 | cell-based format | Scientific Literature | |
18. | ALA4254617 | F | Induction of apoptosis in human HeLa cells assessed as live cells at 50 nM after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 96.5%) | Homo sapiens | 2 | ALA4251633 | cell-based format | Scientific Literature | |
19. | ALA4254618 | F | Induction of apoptosis in human HeLa cells assessed as early apoptotic cells at 50 nM after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 0.7%) | Homo sapiens | 2 | ALA4251633 | cell-based format | Scientific Literature | |
20. | ALA4254619 | F | Induction of apoptosis in human HeLa cells assessed as late apoptotic cells at 50 nM after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 2%) | Homo sapiens | 2 | ALA4251633 | cell-based format | Scientific Literature |