| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4275380 | B | Inhibition of yeast 20S proteasome beta1 subunit using fluorescent substrate pretreated for 30 mins followed by substrate addition and measured after 60 mins by fluorescence assay | Saccharomyces cerevisiae | 7 | single protein format | Scientific Literature | ||
| 2. | ALA4275381 | B | Inhibition of yeast 20S proteasome beta2 subunit using SUC-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured after 60 mins by fluorescence assay | Saccharomyces cerevisiae | 7 | single protein format | Scientific Literature | ||
| 3. | ALA4275382 | B | Inhibition of yeast 20S proteasome beta5 subunit using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate addition and measured after 60 mins by fluorescence assay | Saccharomyces cerevisiae | 7 | assay format | Scientific Literature | ||
| 4. | ALA4275383 | F | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 5. | ALA4275386 | B | Inhibition of 20S proteasome beta5 subunit in human MCF7 cells assessed as accumulation of ubiuitinated protein at 1 to 10 uM after 9.5 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4275387 | F | Induction of apoptosis in human Jurkat cells after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4275388 | F | Cell cycle arrest in human Jurkat cells assessed as accumulation at G2/M phase at 0.1 to 1 uM after 10 hrs by Vybrant DyeCycle Orange staining based flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4275389 | B | Inhibition of 20S proteasome beta5 subunit in human MCF7 cells using Suc-LLVY-AMC as substrate pretreated for 1 hr followed by compound washout and cell lysis prior to substrate addition measured after 1 hr by fluorescence assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 9. | ALA4275391 | B | Inhibition of human immunoproteasome beta5 subunit using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured after 60 mins by fluorescence assay | Homo sapiens | 7 | single protein format | Scientific Literature |
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