| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4258036 | ADME | Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 18 | ALA4257457 | cell-based format | Scientific Literature | |
| 2. | ALA4258037 | Binding | Inhibition of Marburg virus envelope glycoprotein-mediated cell entry in rVSIV-deltaG-MarV-GP pseuotype virus infected HEK293 cells after 24 hrs post transfection by luciferase reporter gene assay | Marburgvirus | 18 | ALA4257457 | cell-based format | Scientific Literature | |
| 3. | ALA4258038 | Binding | Inhibition of Vesicular stomatitis Indiana virus envelope glycoprotein G-mediated cell entry in rVSIV-deltaG-G pseudotype virus infected HEK293 cells after 24 hrs post transfection by luciferase reporter gene assay | Vesicular stomatitis Indiana virus | 18 | ALA4257457 | cell-based format | Scientific Literature | |
| 4. | ALA4258039 | Toxicity | Selectivity index, ratio of CC50 for HEK293 cells to IC50 for Marburg virus envelope glycoprotein-mediated cell entry in rVSIV-deltaG-MarV-GP pseuotype virus infected HEK293 cells | 18 | ALA4257457 | assay format | Scientific Literature | ||
| 5. | ALA4258040 | Binding | Selectivity ratio of IC50 for Marburg virus envelope glycoprotein-mediated cell entry in rVSIV-deltaG-MarV-GP pseuotype virus infected HEK293 cells to IC50 for Vesicular stomatitis Indiana virus envelope glycoprotein-mediated cell entry in rVSIV-deltaG-G pseudotype virus infected HEK293 cells | 18 | ALA4257457 | assay format | Scientific Literature | ||
| 6. | ALA4262058 | Functional | Antiviral activity against Influenza A virus (A/Puerto Rico/8/34(H1N1)) infected in MDCK cells assessed as reduction in viral titer preincubated with cells for 1 hr followed by viral inoculation and measured after 48 hrs by hemagglutination test | Influenza A virus | 28 | ALA4261492 | organism-based format | Scientific Literature | |
| 7. | ALA4262059 | ADME | Cytotoxicity against MDCK cells after 48 hrs by MTT assay | Canis lupus familiaris | 28 | ALA4261492 | cell-based format | Scientific Literature | |
| 8. | ALA4262060 | Toxicity | Selectivity index, ratio of CC50 for MDCK cells to EC50 for Influenza A virus (A/Puerto Rico/8/34(H1N1)) | 28 | ALA4261492 | assay format | Scientific Literature |
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