| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4360918 | F | Bactericidal activity against vancomycin-resistant Staphylococcus aureus HIP11714 at 10 times MIC measured up to 24 hrs by time kill assay | Staphylococcus aureus | 2 | organism-based format | Scientific Literature | ||
| 2. | ALA4404633 | F | Antibacterial activity against Enterococcus faecium ET60 by broth microdilution method | Enterococcus faecium | 4 | organism-based format | Scientific Literature | ||
| 3. | ALA4404634 | F | Antibacterial activity against Streptococcus faecalis by broth microdilution method | Enterococcus faecalis | 4 | organism-based format | Scientific Literature | ||
| 4. | ALA4404635 | F | Antibacterial activity against Enterococcus faecium ET6 by broth microdilution method | Enterococcus faecium | 4 | organism-based format | Scientific Literature | ||
| 5. | ALA4404636 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus SA14 by broth microdilution method | Staphylococcus aureus | 4 | organism-based format | Scientific Literature | ||
| 6. | ALA4404637 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus SA11 by broth microdilution method | Staphylococcus aureus | 4 | organism-based format | Scientific Literature | ||
| 7. | ALA4404638 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus SA86 by broth microdilution method | Staphylococcus aureus | 4 | organism-based format | Scientific Literature | ||
| 8. | ALA4404639 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus SA88 by broth microdilution method | Staphylococcus aureus | 4 | organism-based format | Scientific Literature | ||
| 9. | ALA4404640 | F | Antibacterial activity against Staphylococcus aureus ATCC 29213 by broth microdilution method | Staphylococcus aureus | 4 | organism-based format | Scientific Literature | ||
| 10. | ALA4404641 | F | Antibacterial activity against Enterococcus faecalis ATCC 29212 by broth microdilution method | Enterococcus faecalis | 4 | organism-based format | Scientific Literature | ||
| 11. | ALA4404642 | F | Bactericidal activity against Staphylococcus aureus ATCC 29213 incubated prior to replating on agar plate measured after overnight incubation | Staphylococcus aureus | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA4404643 | F | Bactericidal activity against Enterococcus faecalis ATCC 29212 incubated prior to replating on agar plate measured after overnight incubation | Enterococcus faecalis | 2 | organism-based format | Scientific Literature | ||
| 13. | ALA4404644 | F | Bactericidal activity against Staphylococcus aureus ATCC 29213 assessed as reduction in bacterial load at 4 to 8 ug/ml preincubated for up to 24 hrs followed by subculturing on LB agar plate by time-kill assay | Staphylococcus aureus | 2 | organism-based format | Scientific Literature | ||
| 14. | ALA4404647 | F | Bactericidal activity against Enterococcus faecalis ATCC 29212 assessed as reduction in bacterial load at 16 ug/ml preincubated for up to 24 hrs followed by subculturing on LB agar plate by time-kill assay | Enterococcus faecalis | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4404648 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 infected in Galleria mellonella larvae assessed as increase in larvae survival at 50 mg/kg measured up to 72 hrs post-infection | Staphylococcus aureus | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA4404649 | F | Antibacterial activity against daptomycin-resistant Staphylococcus aureus SA11 infected in Galleria mellonella larvae assessed as increase in larvae survival at 50 mg/kg measured up to 72 hrs post-infection | Staphylococcus aureus | 2 | organism-based format | Scientific Literature | ||
| 17. | ALA4404650 | F | Antibacterial activity against daptomycin-resistant Staphylococcus aureus SA11 infected in NIH mouse model of neutropenic thigh infection assessed reduction in bacterial level in thigh at 50 mg/kg, sc administered at 2 and 12 hrs post infection and measured at 48 to 60 hrs post-infection | Staphylococcus aureus | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA4404651 | F | Antibacterial activity against Staphylococcus aureus USA300 infected in Balb/c mouse model of sepsis assessed as mouse survival at 0.925 mg/kg, sc administered twice daily for 5 days starting from 1 hr post-infection relative to control | Staphylococcus aureus | 2 | organism-based format | Scientific Literature | ||
| 19. | ALA4404652 | F | Antibacterial activity against Staphylococcus aureus USA300 infected in Balb/c mouse model of sepsis assessed as bacterial eradication in kidney at 1.25 mg/kg, sc administered twice daily for 3 days starting from 1 hr post-infection followed by subculturing on LB agar plate and measured after overnight incubation | Staphylococcus aureus | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA4404653 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 infected in iv dosed CD-1 ICR mouse administered as single dose measured after 7 days | Staphylococcus aureus | 2 | organism-based format | Scientific Literature |
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