# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4268221 | B | Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by ion exchange filter paper method | Homo sapiens | 29 | single protein format | Scientific Literature | ||
2. | ALA4268222 | B | Inhibition of HDAC1 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and measured for 1.5 hrs at 15 mins time interval by fluorescence assay | Homo sapiens | 23 | single protein format | Scientific Literature | ||
3. | ALA4268223 | B | Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and measured for 1.5 hrs at 15 mins time interval by fluorescence assay | Homo sapiens | 23 | single protein format | Scientific Literature | ||
4. | ALA4268226 | B | Inhibition of human JAK3 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by ion exchange filter paper method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA4268227 | B | Inhibition of human TYK2 using KKSRGDYMTMQIG as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by ion exchange filter paper method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA4268228 | B | Inhibition of human JAK1 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by ion exchange filter paper method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
7. | ALA4268229 | B | Selectivity ratio of IC50 for human JAK1 to IC50 for human JAK2 | Homo sapiens | 1 | assay format | Scientific Literature | ||
8. | ALA4268230 | B | Selectivity ratio of IC50 for human JAK3 to IC50 for human JAK2 | Homo sapiens | 1 | assay format | Scientific Literature | ||
9. | ALA4268231 | B | Selectivity ratio of IC50 for human TYK2 to IC50 for human JAK2 | Homo sapiens | 1 | assay format | Scientific Literature | ||
10. | ALA4268233 | F | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
11. | ALA4268234 | F | Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
12. | ALA4268235 | F | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
13. | ALA4268236 | F | Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
14. | ALA4268237 | A | Antiproliferative activity against human AC10 cells after 72 hrs by MTT assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
15. | ALA4268238 | A | Antiproliferative activity against mouse TAMH cells after 72 hrs by MTT assay | Mus musculus | 20 | cell-based format | Scientific Literature | ||
16. | ALA4268239 | T | Selectivity index, ratio of CC50 for human AC10 cells to IC50 for human HCT116 cells | Homo sapiens | 18 | assay format | Scientific Literature | ||
17. | ALA4268240 | T | Selectivity index, ratio of CC50 for mouse TAMH cells to IC50 for human HCT116 cells | 18 | assay format | Scientific Literature | |||
18. | ALA4268241 | T | Selectivity index, ratio of CC50 for human AC10 cells to IC50 for human MDA-MB-231 cells | Homo sapiens | 19 | assay format | Scientific Literature | ||
19. | ALA4268242 | T | Selectivity index, ratio of CC50 for mouse TAMH cells to IC50 for human MDA-MB-231 cells | 19 | assay format | Scientific Literature | |||
20. | ALA4268243 | T | Selectivity index, ratio of CC50 for human AC10 cells to IC50 for human MCF7 cells | Homo sapiens | 19 | assay format | Scientific Literature |