# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4268682 | P | Lipophilicity, log D of the compound at pH 7.4 by HPLC analysis | 45 | small-molecule physicochemical format | Scientific Literature | |||
2. | ALA4268683 | B | Inhibition of recombinant human N-terminal His6-tagged SYK expressed in baculovirus expression system using Biotin-AAAEEIYGEI as substrate after 60 mins by TR-FRET assay | Homo sapiens | 48 | assay format | Scientific Literature | ||
3. | ALA4268684 | B | Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide substrate addition after 120 mins by fluorescence polarization assay | Homo sapiens | 46 | protein complex format | Scientific Literature | ||
4. | ALA4268685 | B | Inhibition of SYK in human Ramos B cells assessed as reduction in anti-human IgM Fab2 fragment-induced ERK phosphorylation preincubated for 30 mins followed by IgM stimulation for 2 hrs by electro-chemiluminescence assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
5. | ALA4268689 | A | Drug uptake in human skin epidermal layer administered topically after 6 hrs by LC-MS/MS analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
6. | ALA4268690 | A | Drug uptake in human skin dermal layer administered topically after 6 hrs by LC-MS/MS analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature |