# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4259039 | B | Inhibition of recombinant human full-length N-terminal GST-fused/His6-tagged IKKbeta (M1 to S756 residues) expressed in Sf9 insect cells using ERLLDDRHDSGLDSMKDEE peptide as substrate measured after 60 mins by ADP-Glo kinase assay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
2. | ALA4259040 | B | Inhibition of recombinant human full-length N-terminal GST-fused/His6-tagged IKKepsilon (M1 to V716 residues) expressed in Sf9 insect cells using ERLLDDRHDSGLDSMKDEE peptide as substrate measured after 60 mins by ADP-Glo kinase assay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
3. | ALA4259041 | B | Inhibition of recombinant human full-length N-terminal GST-fused/His6-tagged NIK (M1 to P947 residues) expressed in Sf9 insect cells using AKDVDQGSLCTSFVGTLQY peptide as substrate measured after 60 mins by ADP-Glo kinase assay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
4. | ALA4259042 | B | Inhibition of recombinant full length human His-tagged IKKalpha expressed in baculovirus expression system using ERLLDDRHDSGLDSMKDEE peptide as substrate measured after 60 mins by ADP-Glo kinase assay | Homo sapiens | 45 | assay format | Scientific Literature | ||
5. | ALA4259043 | B | Inhibition of NIK-induced NFkappaB activation in human EJM cells at 20 uM after 6 hrs by dual luciferase reporter gene assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4259048 | B | Inhibition of NFkappaB activation in human MDA-MB-231 cells at 50 uM after 6 hrs by dual luciferase reporter gene assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
7. | ALA4259051 | B | Inhibition of NFkappaB activation in human SKBR3 cells at 50 uM after 6 hrs by dual luciferase reporter gene assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA4259054 | A | Cytotoxicity against human MDA-MB-231 cells assessed as cell viability at 50 uM after 6 hrs by CellTiter Glo luminescent assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
9. | ALA4259057 | A | Cytotoxicity against human EJM cells assessed as cell viability at 20 uM after 6 hrs by CellTiter Glo luminescent assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA4259062 | A | Cytotoxicity against human SKBR3 cells assessed as cell viability at 50 uM after 6 hrs by CellTiter Glo luminescent assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature |