# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4276505 | F | Antiviral activity against Influenza A virus A/goose/Guangdong/SH7/2013(H5N1) infected in chicken embryo fibroblasts assessed as reduction in cytopathic effect after 48 hrs by CCK-8 assay | Influenza A virus | 28 | ALA4270670 | organism-based format | Scientific Literature | |
2. | ALA4276506 | F | Antiviral activity against Influenza A virus A/Chicken/Hebei/LZF/2014(H5N2) infected in chicken embryo fibroblasts assessed as reduction in cytopathic effect after 48 hrs by CCK-8 assay | Influenza A virus | 28 | ALA4270670 | organism-based format | Scientific Literature | |
3. | ALA4276507 | F | Antiviral activity against Influenza A virus A/duck/Guangdong/674/2014(H5N6) infected in chicken embryo fibroblasts assessed as reduction in cytopathic effect after 48 hrs by CCK-8 assay | Influenza A virus | 28 | ALA4270670 | organism-based format | Scientific Literature | |
4. | ALA4276508 | F | Antiviral activity against Influenza A virus A/goose/Jiangsu/1306/2014(H5N8) infected in chicken embryo fibroblasts assessed as reduction in cytopathic effect after 48 hrs by CCK-8 assay | Influenza A virus | 28 | ALA4270670 | organism-based format | Scientific Literature | |
5. | ALA4276509 | A | Cytotoxicity against chicken embryo fibroblasts assessed as reduction in cell viability after 48 hrs by CCK-8 assay | Gallus gallus | 28 | ALA4270670 | cell-based format | Scientific Literature | |
6. | ALA4276510 | F | Antiviral activity against Influenza A virus (A/Puerto Rico/8/34(H1N1)) infected in MDCK cells after 2 days by plaque reduction assay | Influenza A virus | 8 | ALA4270670 | organism-based format | Scientific Literature | |
7. | ALA4276511 | F | Antiviral activity against Influenza A virus (A/Wisconsin/67/2005(H3N2)) infected in MDCK cells after 2 days by plaque reduction assay | Influenza A virus (A/Wisconsin/67/2005(H3N2)) | 8 | ALA4270670 | organism-based format | Scientific Literature | |
8. | ALA4276512 | F | Antiviral activity against Influenza B virus (B/Lee/40) infected in MDCK cells after 3 days by plaque reduction assay | Influenza B virus | 8 | ALA4270670 | organism-based format | Scientific Literature | |
9. | ALA4276513 | A | Cytotoxicity against MDCK cells assessed as reduction in cell viability after 48 hrs by MTT assay | Canis lupus familiaris | 8 | ALA4270670 | cell-based format | Scientific Literature | |
10. | ALA4276514 | B | Inhibition of Influenza A virus A/duck/Guangdong/674/2014(H5N6) neuraminidase N6 using fluorogenic MUNANA as substrate preincubated for 10 mins followed by substrate addition measured after 40 to 60 mins by fluorescence-based assay | Influenza A virus | 13 | ALA4270670 | single protein format | Scientific Literature | |
11. | ALA4276515 | B | Inhibition of Influenza A virus A/goose/Guangdong/SH7/2013(H5N1) neuraminidase N1 using fluorogenic MUNANA as substrate preincubated for 10 mins followed by substrate addition measured after 40 to 60 mins by fluorescence-based assay | Influenza A virus | 13 | ALA4270670 | assay format | Scientific Literature | |
12. | ALA4276516 | B | Inhibition of Influenza A virus A/Chicken/Hebei/LZF/2014(H5N2) neuraminidase N2 using fluorogenic MUNANA as substrate preincubated for 10 mins followed by substrate addition measured after 40 to 60 mins by fluorescence-based assay | Influenza A virus | 13 | ALA4270670 | assay format | Scientific Literature | |
13. | ALA4276517 | B | Inhibition of Influenza A virus A/goose/Jiangsu/1306/2014(H5N8) neuraminidase N8 using fluorogenic MUNANA as substrate preincubated for 10 mins followed by substrate addition measured after 40 to 60 mins by fluorescence-based assay | Influenza A virus | 13 | ALA4270670 | single protein format | Scientific Literature | |
14. | ALA4276518 | B | Inhibition of Influenza A virus A/Anhui/1/2005(H5N1) neuraminidase N1 H274Y mutant using fluorogenic MUNANA as substrate preincubated for 10 mins followed by substrate addition measured after 40 to 60 mins by fluorescence-based assay | Influenza A virus | 13 | ALA4270670 | single protein format | Scientific Literature | |
15. | ALA4276519 | B | Inhibition of Influenza A virus A/California/04/2009 neuraminidase N1 using fluorogenic MUNANA as substrate preincubated for 10 mins followed by substrate addition measured after 40 to 60 mins by fluorescence-based assay | Influenza A virus (A/California/04/2009(H1N1)) | 4 | ALA4270670 | assay format | Scientific Literature | |
16. | ALA4276520 | F | Antiviral activity against Influenza A virus H5N2 infected in specific pathogen free embryonated egg assessed as survival rate at 10 mM preincubated for 1 hr prior to inoculation measured after 48 hrs (Rvb = 0%) | Influenza A virus | 2 | ALA4270670 | organism-based format | Scientific Literature | |
17. | ALA4276521 | F | Antiviral activity against Influenza A virus H5N2 infected in specific pathogen free embryonated egg assessed as survival rate at 2.5 mM preincubated for 1 hr prior to inoculation measured after 48 hrs (Rvb = 0%) | Influenza A virus | 2 | ALA4270670 | organism-based format | Scientific Literature | |
18. | ALA4276522 | F | Antiviral activity against Influenza A virus H5N2 infected in specific pathogen free embryonated egg assessed as survival rate at 0.625 mM preincubated for 1 hr prior to inoculation measured after 48 hrs (Rvb = 0%) | Influenza A virus | 2 | ALA4270670 | organism-based format | Scientific Literature | |
19. | ALA4276523 | F | Antiviral activity against Influenza A virus H5N2 infected in specific pathogen free embryonated egg assessed as survival rate at 0.156 mM preincubated for 1 hr prior to inoculation measured after 48 hrs (Rvb = 0%) | Influenza A virus | 2 | ALA4270670 | organism-based format | Scientific Literature | |
20. | ALA4276524 | F | Antiviral activity against Influenza A virus H5N2 infected in specific pathogen free embryonated egg assessed as survival rate at 0.039 mM preincubated for 1 hr prior to inoculation measured after 48 hrs (Rvb = 0%) | Influenza A virus | 2 | ALA4270670 | organism-based format | Scientific Literature |