| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4255964 | B | Binding affinity to human His6-tagged BRD4 BD1 (N44 to E168 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as change in melting temperature at 200 uM after 30 mins by SYPRO Orange-dye based fluorescence thermal shift assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 2. | ALA4255965 | B | Inhibition of human His6-tagged BRD4 BD1 (N44 to E168 residues) expressed in Escherichia coli BL21 (DE3) cells at 20 uM using H-SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRK-Biotin-OH as substrate after 2.5 hrs by AlphaScreen assay relative to control | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 3. | ALA4255966 | B | Inhibition of human His6-tagged BRD4 BD1 (N44 to E168 residues) expressed in Escherichia coli BL21 (DE3) cells using H-SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRK-Biotin-OH as substrate after 2.5 hrs by AlphaScreen assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 4. | ALA4255967 | B | Binding affinity to human His6-tagged BRD4 BD1 (N44 to E168 residues) expressed in Escherichia coli BL21 (DE3) cells by isothermal titration calorimetry method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4255968 | F | Antiproliferative activity against human C4-2B cells after 96 hrs by Cell-Titer glo reagent based luminescence assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 6. | ALA4255969 | F | Antiproliferative activity against human LNCAP cells after 96 hrs by Cell-Titer glo reagent based luminescence assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 7. | ALA4255970 | F | Antiproliferative activity against human 22Rv1 cells after 96 hrs by Cell-Titer glo reagent based luminescence assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 8. | ALA4255971 | F | Antiproliferative activity against human PC3 cells after 96 hrs by Cell-Titer glo reagent based luminescence assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 9. | ALA4255973 | F | Antiproliferative activity against human DU145 cells after 96 hrs by Cell-Titer glo reagent based luminescence assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 10. | ALA4255991 | B | Inhibition of human His6-tagged CBP (R1081 to G1197 residues)/EP300 (A1040 to G1161 residues) expressed in Escherichia coli BL21 (DE3) cells by SYPRO Orange-dye based fluorescence thermal shift assay | Homo sapiens | 5 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!