# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4257240 | Binding | Inhibition of human Eya3 isoform 2 (127 to 573 residues) incubated for 30 mins by p-nitrophenylphosphate assay | Homo sapiens | 14 | ALA4257222 | assay format | Patent Bioactivity Data | |
2. | ALA4257259 | Functional | Inhibition of tube formation of HUVEC by matrigel tube-formation assay | Homo sapiens | 8 | ALA4257222 | cell-based format | Patent Bioactivity Data | |
3. | ALA4257265 | Functional | Inhibition of sprouting in mouse aorta cultured in collagen gels at 7.5 uM by aortic ring sprouting assay | Mus musculus | 7 | ALA4257222 | tissue-based format | Patent Bioactivity Data | |
4. | ALA4257266 | Functional | Inhibition of branching in mouse aorta cultured in collagen gels assessed as reduction in number of branch-points at 7.5 uM by aortic ring sprouting assay | Mus musculus | 7 | ALA4257222 | tissue-based format | Patent Bioactivity Data | |
5. | ALA4422501 | Binding | Inhibition of poly-histidine and GST-tagged full length human Eya3 isoform 2 (127 to 573 residues) using para-nitrophenol phosphate substrate incubated for 30 mins | Homo sapiens | 14 | ALA4421732 | single protein format | Patent Bioactivity Data | |
6. | ALA4422523 | Functional | Inhibition of micro-vessel branching in C57BL16 mouse aorta cultured in collagen gels assessed as reduction in aortic ring sprouting at 7.5 uM by aortic ring sprouting assay | Mus musculus | 7 | ALA4421732 | tissue-based format | Patent Bioactivity Data | |
7. | ALA4422524 | Functional | Inhibition of micro-vessel branching in C57BL16 mouse aorta cultured in collagen gels assessed as reduction in initial sprouting at 7.5 uM by aortic ring sprouting assay | Mus musculus | 7 | ALA4421732 | tissue-based format | Patent Bioactivity Data | |
8. | ALA4422525 | Functional | Inhibition of micro-vessel branching in C57BL16 mouse aorta cultured in collagen gels assessed as attenuation of branching at 7.5 uM by aortic ring sprouting assay | Mus musculus | 7 | ALA4421732 | tissue-based format | Patent Bioactivity Data |