# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4254829 | P | Octanol-water partition coefficient, log P of the compound after 10 mins | 6 | ALA4251644 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA4254830 | A | Drug uptake in human HepG2 cells at 5 uM after 2 hrs by confocal microscopy | Homo sapiens | 6 | ALA4251644 | cell-based format | Scientific Literature | |
3. | ALA4254831 | A | Drug uptake in mouse B16F10 cells assessed as localization in mitochondria at 5 uM after 1.5 hrs by MitoTracker Green staining-based fluorescence assay | Mus musculus | 6 | ALA4251644 | mitochondrion format | Scientific Literature | |
4. | ALA4254832 | T | Toxicity in human HepG2 cells up to 5 uM incubated in dark for 24 hrs by MTT assay | Homo sapiens | 6 | ALA4251644 | cell-based format | Scientific Literature | |
5. | ALA4254833 | T | Toxicity in human MCF7 cells up to 5 uM incubated in dark for 24 hrs by MTT assay | Homo sapiens | 6 | ALA4251644 | cell-based format | Scientific Literature | |
6. | ALA4254834 | T | Toxicity in mouse B16F10 cells up to 5 uM incubated in dark for 24 hrs by MTT assay | Mus musculus | 6 | ALA4251644 | cell-based format | Scientific Literature | |
7. | ALA4254835 | F | Photodynamic anticancer activity in human HepG2 cells preincubated for 2 hrs followed by light exposure at 27 J/cm2 for 30 mins and subsequent incubation for 24 hrs by MTT assay | Homo sapiens | 6 | ALA4251644 | cell-based format | Scientific Literature | |
8. | ALA4254836 | F | Photodynamic anticancer activity in human MCF7 cells preincubated for 2 hrs followed by light exposure at 27 J/cm2 for 30 mins and subsequent incubation for 24 hrs by MTT assay | Homo sapiens | 6 | ALA4251644 | cell-based format | Scientific Literature | |
9. | ALA4254837 | F | Photodynamic anticancer activity in mouse B16F10 cells preincubated for 2 hrs followed by light exposure at 27 J/cm2 for 30 mins and subsequent incubation for 24 hrs by MTT assay | Mus musculus | 6 | ALA4251644 | cell-based format | Scientific Literature | |
10. | ALA4254843 | A | Drug uptake in mouse B16F10 cells assessed as localization in lysosomes at 5 uM after 1.5 hrs by LysoTracker staining-based fluorescence assay | Mus musculus | 6 | ALA4251644 | subcellular format | Scientific Literature | |
11. | ALA4381499 | F | Photo-activated cytotoxicity against mouse B16-F10-luc2 cells assessed as cell viability at 1 uM preincubated for 3 hrs followed by compound washout and subsequent 22.8 J cm'-2 light irradiation for 60 secs measured after 21 hrs by MTT assay relative to control | Mus musculus | 4 | ALA4376887 | cell-based format | Scientific Literature | |
12. | ALA4381508 | F | Induction of ROS generation in ethanol assessed as reduction in DPBF absorbance at 410 nm at 1 uM preincubated for 10 mins followed by 342 J cm'-2 light irradiation for 15 mins and measured at 5 mins interval for 15 mins by spectrometric method | 3 | ALA4376887 | assay format | Scientific Literature | ||
13. | ALA4381509 | F | Induction of singlet oxygen generation in ethanol at 1 uM preincubated for 10 mins followed by 342 J cm'-2 light irradiation for 15 mins and measured at 5 mins interval for 15 mins by spectrometric method | 2 | ALA4376887 | assay format | Scientific Literature |