#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4265762	Binding	Inhibition of ACAT in arterial homogenates isolated from 1% cholesterol fed New Zealand White rabbit assessed as reduction in cholesteryl oleate formation incubated for 5 mins in presence of [14C]-oleoyl-CoA and BSA complex by TLC method	Oryctolagus cuniculus	21	ALA4261657	tissue-based format	Scientific Literature
2.	ALA4265763	Binding	Inhibition of ACAT in New Zealand White rabbit intestinal microsomes assessed as reduction in cholesteryl oleate formation incubated for 3 mins in presence of [14C]-oleoyl-CoA and BSA complex by TLC method	Oryctolagus cuniculus	21	ALA4261657	assay format	Scientific Literature
3.	ALA4265764	Binding	Selectivity ratio of IC50 for ACAT in New Zealand White rabbit intestinal microsomes to IC50 for ACAT in arterial homogenates isolated from 1% cholesterol fed New Zealand White rabbit	Oryctolagus cuniculus	19	ALA4261657	tissue-based format	Scientific Literature
4.	ALA4265765	Binding	Inhibition of ACAT in human J774A.1 cells assessed as reduction in esterified-cholesterol accumulation after 18 hrs in presence of 25-hydroxycholesterol by cholesterol E-test analysis	Homo sapiens	21	ALA4261657	cell-based format	Scientific Literature
5.	ALA4265766	Physicochemical	Aqueous solubility of the compound at pH 1.2		5	ALA4261657	small-molecule physicochemical format	Scientific Literature
6.	ALA4265767	ADME	Tmax in Sprague-Dawley rat at 30 mg/kg, po by LC/MS analysis	Rattus norvegicus	3	ALA4261657	organism-based format	Scientific Literature
7.	ALA4265768	ADME	Cmax in Sprague-Dawley rat at 30 mg/kg, po by LC/MS analysis	Rattus norvegicus	3	ALA4261657	organism-based format	Scientific Literature
8.	ALA4265769	ADME	Half life in Sprague-Dawley rat at 30 mg/kg, po by LC/MS analysis	Rattus norvegicus	3	ALA4261657	organism-based format	Scientific Literature
9.	ALA4265770	ADME	AUC (0 to infinity) in Sprague-Dawley rat at 30 mg/kg, po by LC/MS analysis	Rattus norvegicus	3	ALA4261657	organism-based format	Scientific Literature
10.	ALA4265771	Functional	Antiatherosclerotic activity in Bio F1B hamster model of diet-induced atherosclerosis assessed as reduction in lipid accumulation areas in aortic arch at 3 mg/kg/day added to chow pellets by oil red O staining based assay relative to control	Cricetinae	3	ALA4261657	organism-based format	Scientific Literature
11.	ALA4265772	Functional	Antiatherosclerotic activity in Bio F1B hamster model of diet-induced atherosclerosis assessed as reduction in lipid accumulation areas in aortic arch at 10 mg/kg/day added to chow pellets by oil red O staining based assay relative to control	Cricetinae	3	ALA4261657	organism-based format	Scientific Literature
12.	ALA4265774	Functional	Antiatherosclerotic activity in Bio F1B hamster model of diet-induced atherosclerosis assessed as reduction in total plasma cholesterol at 3 mg/kg/day added to chow pellets relative to control	Cricetinae	3	ALA4261657	organism-based format	Scientific Literature
13.	ALA4265775	Functional	Antiatherosclerotic activity in Bio F1B hamster model of diet-induced atherosclerosis assessed as reduction in total plasma cholesterol at 10 mg/kg/day added to chow pellets relative to control	Cricetinae	3	ALA4261657	organism-based format	Scientific Literature
14.	ALA4265777	Functional	Antiatherosclerotic activity in Bio F1B hamster model of diet-induced atherosclerosis assessed as reduction in CE to FC ratio in liver at 1 to 30 mg/kg/day added to chow pellets	Cricetinae	2	ALA4261657	organism-based format	Scientific Literature
15.	ALA4265778	Toxicity	Toxicity in Bio F1B hamster model of diet-induced atherosclerosis assessed as reduction in CE to FC ratio in adrenal gland at 1 to 30 mg/kg/day added to chow pellets	Cricetinae	2	ALA4261657	organism-based format	Scientific Literature
16.	ALA4265783	Toxicity	Genotoxicity in Salmonella typhimurium TA98 by Ames test	Salmonella enterica subsp. enterica serovar Typhimurium	3	ALA4261657	organism-based format	Scientific Literature
17.	ALA4265784	Toxicity	Genotoxicity in Salmonella typhimurium TA100 by Ames test	Salmonella enterica subsp. enterica serovar Typhimurium	3	ALA4261657	organism-based format	Scientific Literature
18.	ALA4265785	Toxicity	Genotoxicity in Salmonella typhimurium TA1537 by Ames test	Salmonella enterica subsp. enterica serovar Typhimurium	3	ALA4261657	organism-based format	Scientific Literature
19.	ALA4265786	Toxicity	Genotoxicity in Salmonella typhimurium TA1535 by Ames test	Salmonella enterica subsp. enterica serovar Typhimurium	3	ALA4261657	organism-based format	Scientific Literature
20.	ALA4265787	Toxicity	Genotoxicity in Escherichia coli WPuvrA by Ames test	Escherichia coli	3	ALA4261657	organism-based format	Scientific Literature