| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4255803 | B | Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pigment inhibition assay | Staphylococcus aureus subsp. aureus str. Newman | 39 | ALA4251700 | single protein format | Scientific Literature | |
| 2. | ALA4255804 | B | Inhibition of Staphylococcus aureus Newman Hi6-tagged CrtN expressed in Escherichia coli BL21(DE3))/pET28a::CrtN assessed as reduction in staphyloxanthin levels using diapophytoene as substrate after overnight incubation | Staphylococcus aureus subsp. aureus str. Newman | 4 | ALA4251700 | assay format | Scientific Literature | |
| 3. | ALA4255805 | B | Inhibition of CrtN in vancomycin-intermediate Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pigment inhibition assay | Staphylococcus aureus subsp. aureus Mu50 | 4 | ALA4251700 | single protein format | Scientific Literature | |
| 4. | ALA4255806 | B | Inhibition of CrtN in linezolid-resistant Staphylococcus aureus NRS271 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pigment inhibition assay | Staphylococcus aureus | 3 | ALA4251700 | single protein format | Scientific Literature | |
| 5. | ALA4255807 | B | Inhibition of CrtN in methicillin-resistant Staphylococcus aureus USA400 MW2 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pigment inhibition assay | Staphylococcus aureus subsp. aureus MW2 | 4 | ALA4251700 | single protein format | Scientific Literature | |
| 6. | ALA4255808 | B | Inhibition of CrtN in methicillin-resistant Staphylococcus aureus LAC USA300 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pigment inhibition assay | Staphylococcus aureus subsp. aureus USA300 | 4 | ALA4251700 | single protein format | Scientific Literature | |
| 7. | ALA4255809 | B | Inhibition of recombinant human ERG expressed in CHO cells at -80 mV holding potential measured after 3 minutes by automated whole cell patch clamp Qpatch method | Homo sapiens | 6 | ALA4251700 | cell-based format | Scientific Literature | |
| 8. | ALA4255810 | P | Solubility of the compound in water at 10 mg measured after 24 hrs by HPLC method | 6 | ALA4251700 | small-molecule physicochemical format | Scientific Literature | ||
| 9. | ALA4255811 | A | Growth inhibition of Staphylococcus aureus Newman at 0.2 mM incubated overnight measured at 30 mins interval | Staphylococcus aureus | 1 | ALA4251700 | organism-based format | Scientific Literature | |
| 10. | ALA4255812 | A | Growth inhibition of vancomycin-intermediate Staphylococcus aureus Mu50 at 0.2 mM incubated overnight measured at 30 mins interval | Staphylococcus aureus | 1 | ALA4251700 | organism-based format | Scientific Literature | |
| 11. | ALA4255813 | A | Growth inhibition of methicillin-resistant Staphylococcus aureus USA300 LAC at 0.2 mM incubated overnight measured at 30 mins interval | Staphylococcus aureus | 1 | ALA4251700 | organism-based format | Scientific Literature | |
| 12. | ALA4255814 | A | Growth inhibition of methicillin-resistant Staphylococcus aureus USA400 MW2 at 0.2 mM incubated overnight measured at 30 mins interval | Staphylococcus aureus | 1 | ALA4251700 | organism-based format | Scientific Literature | |
| 13. | ALA4255815 | F | Antifungal activity against Trichophyton rubrum after 7 days by broth microdilution method | Trichophyton rubrum | 1 | ALA4251700 | organism-based format | Scientific Literature | |
| 14. | ALA4255816 | F | Antifungal activity against Microsporum gypseum after 7 days by broth microdilution method | Nannizzia gypsea | 1 | ALA4251700 | organism-based format | Scientific Literature | |
| 15. | ALA4255817 | F | Antifungal activity against Trichophyton verrucosum after 7 days | Trichophyton verrucosum | 1 | ALA4251700 | organism-based format | Scientific Literature | |
| 16. | ALA4255818 | F | Antifungal activity against Trichophyton mentagrophytes after 7 days | Trichophyton mentagrophytes | 1 | ALA4251700 | organism-based format | Scientific Literature | |
| 17. | ALA4255819 | B | Inhibition of CrtN in Staphylococcus aureus Newman assessed as H2O2-induced bacterial death by measuring reduction in bacterial survival at 1 uM pretreated for 24 hrs followed by H2O2 addition measured after 30 mins by serial dilution method | Staphylococcus aureus subsp. aureus str. Newman | 1 | ALA4251700 | single protein format | Scientific Literature | |
| 18. | ALA4255820 | B | Inhibition of CrtN in Staphylococcus aureus Mu50 assessed as H2O2-induced bacterial death by measuring reduction in bacterial survival at 1 uM preincubated for 24 hrs followed by H2O2 addition measured after 30 mins by serial dilution method | Staphylococcus aureus subsp. aureus Mu50 | 1 | ALA4251700 | single protein format | Scientific Literature | |
| 19. | ALA4255821 | B | Inhibition of CrtN in Staphylococcus aureus USA300 LAC assessed as H2O2-induced bacterial death by measuring reduction in bacterial survival at 1 uM preincubated for 24 hrs followed by H2O2 addition measured after 30 mins by serial dilution method | Staphylococcus aureus subsp. aureus USA300 | 1 | ALA4251700 | single protein format | Scientific Literature | |
| 20. | ALA4255822 | B | Inhibition of CrtN in Staphylococcus aureus USA400 MW2 assessed as H2O2-induced bacterial death by measuring reduction in bacterial survival at 1 uM preincubated for 24 hrs followed by H2O2 addition measured after 30 mins by serial dilution method | Staphylococcus aureus subsp. aureus MW2 | 1 | ALA4251700 | single protein format | Scientific Literature |
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