# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4274026 | Functional | Anticancer activity against human MCF7 cells assessed as cell viability at 10 uM after 72 hrs by sulforhodamine B assay relative to control | Homo sapiens | 34 | ALA4270591 | cell-based format | Scientific Literature | |
2. | ALA4274027 | Functional | Anticancer activity against human MCF7 cells assessed as cell viability at 30 uM after 72 hrs by sulforhodamine B assay relative to control | Homo sapiens | 34 | ALA4270591 | cell-based format | Scientific Literature | |
3. | ALA4274028 | Functional | Anticancer activity against human Hs 578T cells assessed as cell viability at 10 uM after 72 hrs by sulforhodamine B assay relative to control | Homo sapiens | 20 | ALA4270591 | cell-based format | Scientific Literature | |
4. | ALA4274029 | Functional | Anticancer activity against human Hs 578T cells assessed as cell viability at 30 uM after 72 hrs by sulforhodamine B assay relative to control | Homo sapiens | 20 | ALA4270591 | cell-based format | Scientific Literature | |
5. | ALA4274030 | ADME | Cytotoxicity against human MCF10A cells assessed as cell viability at 10 uM after 72 hrs by sulforhodamine B assay relative to control | Homo sapiens | 20 | ALA4270591 | cell-based format | Scientific Literature | |
6. | ALA4274031 | ADME | Cytotoxicity against human MCF10A cells assessed as cell viability at 30 uM after 72 hrs by sulforhodamine B assay relative to control | Homo sapiens | 20 | ALA4270591 | cell-based format | Scientific Literature | |
7. | ALA4274032 | Functional | Anticancer activity against human MCF7 cells after 72 hrs by sulforhodamine B assay | Homo sapiens | 9 | ALA4270591 | cell-based format | Scientific Literature | |
8. | ALA4274033 | Functional | Anticancer activity against human Hs 578T cells after 72 hrs by sulforhodamine B assay | Homo sapiens | 9 | ALA4270591 | cell-based format | Scientific Literature | |
9. | ALA4274034 | ADME | Cytotoxicity against human MCF10A cells after 72 hrs by sulforhodamine B assay | Homo sapiens | 9 | ALA4270591 | cell-based format | Scientific Literature | |
10. | ALA4274036 | Functional | Antimigratory activity against human MCF7 cells assessed as reduction in cell migration at half IC50 to IC50 after 12 to 48 hrs by microscopy based wound healing assay | Homo sapiens | 3 | ALA4270591 | cell-based format | Scientific Literature | |
11. | ALA4274037 | Functional | Antiproliferative activity against human MCF7 cells by Brdu incorporation assay | Homo sapiens | 4 | ALA4270591 | cell-based format | Scientific Literature | |
12. | ALA4274038 | Functional | Antiproliferative activity against human MCF7 cells at IC50 after 48 hrs by Brdu incorporation assay relative to control | Homo sapiens | 3 | ALA4270591 | cell-based format | Scientific Literature | |
13. | ALA4274040 | Functional | Induction of apoptosis in human MCF7 cells assessed as increase in early apoptotic cells at IC50 after 48 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry | Homo sapiens | 2 | ALA4270591 | cell-based format | Scientific Literature | |
14. | ALA4274041 | Functional | Induction of apoptosis in human MCF7 cells assessed as increase in late apoptotic cells at IC50 after 48 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry | Homo sapiens | 2 | ALA4270591 | cell-based format | Scientific Literature | |
15. | ALA4274043 | Functional | Induction of apoptosis in human MCF7 cells assessed as increase in cleaved PARP level at IC50 after 24 hrs by Western blot analysis | Homo sapiens | 4 | ALA4270591 | cell-based format | Scientific Literature | |
16. | ALA4274044 | Functional | Induction of apoptosis in human MCF7 cells assessed as increase in Bim level at IC50 after 24 hrs by Western blot analysis | Homo sapiens | 4 | ALA4270591 | cell-based format | Scientific Literature | |
17. | ALA4274045 | Functional | Induction of apoptosis in human MCF7 cells assessed as decrease in Bcl-xL level at IC50 after 24 hrs by Western blot analysis | Homo sapiens | 4 | ALA4270591 | cell-based format | Scientific Literature | |
18. | ALA4274048 | Functional | Cell cycle arrest in human MCF7 cells assessed as DNA fragmentation at IC50 after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4270591 | cell-based format | Scientific Literature | |
19. | ALA4274049 | Functional | Cell cycle arrest in human MCF7 cells assessed as accumulation at sub-G0/G1 phase at IC50 after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4270591 | cell-based format | Scientific Literature | |
20. | ALA4274051 | Binding | Induction of microtubule disruption in human MCF7 cells at IC50 after 12 hrs by DAPI staining based microscopic analysis | Homo sapiens | 3 | ALA4270591 | cell-based format | Scientific Literature |