# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4254161 | B | Inhibition of HDAC1 (unknown origin) | Homo sapiens | 13 | ALA4251618 | single protein format | Scientific Literature | |
2. | ALA4254162 | B | Inhibition of HDAC3 (unknown origin) | Homo sapiens | 4 | ALA4251618 | single protein format | Scientific Literature | |
3. | ALA4254163 | B | Inhibition of HDAC6 (unknown origin) | Homo sapiens | 4 | ALA4251618 | single protein format | Scientific Literature | |
4. | ALA4254164 | B | Inhibition of HDAC8 (unknown origin) | Homo sapiens | 4 | ALA4251618 | single protein format | Scientific Literature | |
5. | ALA4254165 | F | Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay | Homo sapiens | 13 | ALA4251618 | cell-based format | Scientific Literature | |
6. | ALA4254166 | F | Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay | Homo sapiens | 13 | ALA4251618 | cell-based format | Scientific Literature | |
7. | ALA4254167 | F | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay | Homo sapiens | 13 | ALA4251618 | cell-based format | Scientific Literature | |
8. | ALA4254168 | F | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 13 | ALA4251618 | cell-based format | Scientific Literature | |
9. | ALA4254169 | F | Antiproliferative activity against human HuH7 cells after 48 hrs by MTT assay | Homo sapiens | 13 | ALA4251618 | cell-based format | Scientific Literature | |
10. | ALA4254170 | B | Inhibition of HDAC1 in human HepG2 cells assessed as upregulation of acetyl-histone H3 levels after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4251618 | cell-based format | Scientific Literature | |
11. | ALA4254171 | B | Inhibition of HDAC6 in human HepG2 cells assessed as upregulation of acetyl-alpha-tubulin levels after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4251618 | cell-based format | Scientific Literature | |
12. | ALA4254172 | B | Inhibition of HDAC1 in human HepG2 cells assessed as upregulation of acetyl-histone H3 levels at 1 to 2 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4251618 | cell-based format | Scientific Literature | |
13. | ALA4254173 | B | Inhibition of HDAC6 in human HepG2 cells assessed as upregulation of acetyl-alpha-tubulin levels at 1 to 2 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4251618 | cell-based format | Scientific Literature | |
14. | ALA4254174 | F | Cell cycle arrest in human HepG2 cells assessed as increase in accumulation of cells at G2/M phase after 48 hrs by propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | ALA4251618 | cell-based format | Scientific Literature | |
15. | ALA4254175 | F | Antimigratory activity in human HepG2 cells after 24 hrs by wound-healing assay | Homo sapiens | 1 | ALA4251618 | cell-based format | Scientific Literature | |
16. | ALA4254176 | F | Down regulation of cyclin B levels in human HepG2 cells at 0.5 to 1 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4251618 | cell-based format | Scientific Literature | |
17. | ALA4254177 | F | Down regulation of CDK1 levels in human HepG2 cells at 0.5 to 1 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4251618 | cell-based format | Scientific Literature | |
18. | ALA4254178 | F | Antimigratory activity in human HepG2 cells assessed as cell migration rate at 0.5 uM after 24 hrs by wound-healing assay | Homo sapiens | 1 | ALA4251618 | cell-based format | Scientific Literature | |
19. | ALA4254180 | F | Antimetastatic activity in human HepG2 cells assessed as reduction in cell invasion at 0.5 uM after 48 hrs by crystal violet staining-based transwell invasion assay | Homo sapiens | 1 | ALA4251618 | cell-based format | Scientific Literature | |
20. | ALA4254182 | F | Antimetastatic activity in human HepG2 cells assessed as reduction in MMP-2 levels at 0.25 to 0.5 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4251618 | cell-based format | Scientific Literature |