# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4253072 | F | Antiproliferative activity against mouse L1210 cells after 2 days by Coulter counter method | Mus musculus | 19 | ALA4251588 | cell-based format | Scientific Literature | |
2. | ALA4253073 | F | Antiproliferative activity against mouse FM3A cells after 2 days by Coulter counter method | Mus musculus | 19 | ALA4251588 | cell-based format | Scientific Literature | |
3. | ALA4253074 | F | Antiproliferative activity against human CEM cells after 3 days by Coulter counter method | Homo sapiens | 19 | ALA4251588 | cell-based format | Scientific Literature | |
4. | ALA4253075 | F | Antiproliferative activity against human HeLa cells after 4 days by Coulter counter method | Homo sapiens | 19 | ALA4251588 | cell-based format | Scientific Literature | |
5. | ALA4253076 | A | Growth inhibition of resting human PBL after 72 hrs by MTT assay | Homo sapiens | 3 | ALA4251588 | cell-based format | Scientific Literature | |
6. | ALA4253077 | A | Growth inhibition of human PHA-stimulated PBL after 72 hrs by MTT assay | Homo sapiens | 3 | ALA4251588 | cell-based format | Scientific Literature | |
7. | ALA4253078 | B | Inhibition of bovine brain tubulin polymerization in presence of GTP by spectrophotometric analysis | Bos taurus | 7 | ALA4251588 | assay format | Scientific Literature | |
8. | ALA4253079 | B | Inhibition of [3H]colchicine binding to bovine brain tubulin at 5 uM relative to control | Bos taurus | 7 | ALA4251588 | assay format | Scientific Literature | |
9. | ALA4253080 | F | Cell cycle arrest in human HeLa cells assessed as accumulation of cells at G2/M phase at 500 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis | Homo sapiens | 3 | ALA4251588 | cell-based format | Scientific Literature | |
10. | ALA4253081 | F | Cell cycle arrest in human HeLa cells assessed as reduction of cells at G1 phase up to 500 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis | Homo sapiens | 3 | ALA4251588 | cell-based format | Scientific Literature | |
11. | ALA4253082 | F | Cell cycle arrest in human HeLa cells assessed as increase in cells at S phase at 500 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis | Homo sapiens | 3 | ALA4251588 | cell-based format | Scientific Literature | |
12. | ALA4253083 | F | Cell cycle arrest in human HeLa cells assessed as increase in cyclin B1 expression after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4251588 | cell-based format | Scientific Literature | |
13. | ALA4253084 | F | Cell cycle arrest in human HeLa cells assessed as decrease in cyclin B1 expression after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4251588 | cell-based format | Scientific Literature | |
14. | ALA4253085 | F | Cell cycle arrest in human HeLa cells assessed as increase in cdc25c expression at 100 nM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4251588 | cell-based format | Scientific Literature | |
15. | ALA4253086 | F | Cell cycle arrest in human HeLa cells assessed as decrease in Cdk1 Y15 phosphorylated protein level at 250 nM after 24 to 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4251588 | cell-based format | Scientific Literature | |
16. | ALA4253087 | F | Induction of apoptosis in human HeLa cells at 125 to 500 nM after 24 to 48 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 3 | ALA4251588 | cell-based format | Scientific Literature | |
17. | ALA4253088 | F | Induction of mitochondrial depolarization in human HeLa cells at 100 to 250 nM by JC-1 staining-based flow cytometric analysis | Homo sapiens | 1 | ALA4251588 | cell-based format | Scientific Literature | |
18. | ALA4253089 | F | Induction of ROS production in human HeLa cells at 250 nM after 12 to 24 hrs by H2DCFDA staining-based flow cytometric analysis | Homo sapiens | 1 | ALA4251588 | cell-based format | Scientific Literature | |
19. | ALA4253090 | F | Induction of apoptosis in human HeLa cells assessed as increase in cleaved PARP levels by Western blot analysis | Homo sapiens | 1 | ALA4251588 | cell-based format | Scientific Literature | |
20. | ALA4253091 | F | Induction of apoptosis in human HeLa cells assessed as decrease in Bcl-2 levels at 100 to 250 nM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4251588 | cell-based format | Scientific Literature |