| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4253672 | B | Inhibition of GST-tagged LSD1 (2 to 852 residues) (unknown origin) expressed in baculovirus infected sf9 cells preincubated for 15 mins followed by H3K4me2 substrate addition measured after 60 mins by amplex red reagent based HRP enzyme coupled fluorescence assay | Homo sapiens | 46 | ALA4251603 | cell-based format | Scientific Literature | |
| 2. | ALA4253675 | B | Inhibition of MAO-A (unknown origin) using beetle luciferin derived luminogenic substrate preincubated for 15 mins followed by substrate addition measured after 60 mins by MAO-Glo assay | Homo sapiens | 16 | ALA4251603 | single protein format | Scientific Literature | |
| 3. | ALA4253677 | B | Inhibition of MAO-B (unknown origin) using beetle luciferin derived luminogenic substrate preincubated for 15 mins followed by substrate addition measured after 60 mins by MAO-Glo assay | Homo sapiens | 8 | ALA4251603 | single protein format | Scientific Literature | |
| 4. | ALA4253685 | F | Inhibition of colony formation in human THP1 cells at 0.5 uM after 5 mins by light microscopic method relative to control | Homo sapiens | 2 | ALA4251603 | cell-based format | Scientific Literature | |
| 5. | ALA4253687 | B | Stabilization of LSD1 in human THP1 cells assessed as melting temperature at 30 uM after 1 hr by CETSA (Rvb = 46 +/- 1.1 degC) | Homo sapiens | 5 | ALA4251603 | cell-based format | Scientific Literature | |
| 6. | ALA4253688 | B | Inhibition of LSD1 in mouse Hoxa9/Meis1 transformed progenitor cells assessed as induction of granulocytic differentiation at 50 to 100 nM up to 96 hrs by pappenheim staining based assay | Mus musculus | 2 | ALA4251603 | assay format | Scientific Literature | |
| 7. | ALA4253689 | B | Inhibition of LSD1 in mouse Hoxa9/Meis1 transformed progenitor cells assessed as reduction in c-Kit positive cells at 100 nM after 96 hrs by flow cytometry | Mus musculus | 2 | ALA4251603 | cell-based format | Scientific Literature | |
| 8. | ALA4253693 | B | Inhibition of LSD1 in human THP1 cells assessed as increase in CD84+ level at 0.5 uM after 72 hrs by APC/7AAD staining based flow cytometry | Homo sapiens | 7 | ALA4251603 | cell-based format | Scientific Literature |
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