Displacement of [3H]AVP from human vasopressin V1b receptor expressed in CHO cell membranes after 60 mins by TopCount microplate scintillation counting method
Antidepressant like activity in Sprague-Dawley rat assessed as floating time at 3 mg/kg, ip administered at 24, 4 and 0.5 hrs prior to test by forced swimming test
Antidepressant like activity in Sprague-Dawley rat assessed as swimming time at 3 mg/kg, ip administered at 24, 4 and 0.5 hrs prior to test by forced swimming test
Antidepressant like activity in Sprague-Dawley rat assessed as climbing time at 3 mg/kg, ip administered at 24, 4 and 0.5 hrs prior to test by forced swimming test