The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
The page will load shortly, Thanks for your patience!
# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4266687 Binding Displacement of [3H]AVP from human vasopressin V1b receptor expressed in CHO cell membranes after 60 mins by TopCount microplate scintillation counting method Homo sapiens 26 ALA4265879 cell-based format Scientific Literature 2. ALA4266688 Binding Selectivity index, ratio of Ki for human vasopressin V1a receptor to Ki for human vasopressin V1b receptor Homo sapiens 16 ALA4265879 assay format Scientific Literature 3. ALA4266689 Binding Selectivity index, ratio of Ki for human oxytocin receptor to Ki for human vasopressin V1b receptor Homo sapiens 16 ALA4265879 assay format Scientific Literature 4. ALA4266690 ADME Intrinsic clearance in human liver microsomes Homo sapiens 23 ALA4265879 microsome format Scientific Literature 5. ALA4266691 ADME Intrinsic clearance in rat liver microsomes Rattus norvegicus 23 ALA4265879 microsome format Scientific Literature 6. ALA4266692 ADME Elimination half life in rat at 2 mg/kg, iv Rattus norvegicus 4 ALA4265879 organism-based format Scientific Literature 7. ALA4266693 ADME Volume of distribution at steady state in rat at 2 mg/kg, iv Rattus norvegicus 4 ALA4265879 organism-based format Scientific Literature 8. ALA4266694 ADME Clearance in rat plasma at 2 mg/kg, iv Rattus norvegicus 4 ALA4265879 organism-based format Scientific Literature 9. ALA4266695 ADME Oral bioavailability in rat at 10 mg/kg Rattus norvegicus 3 ALA4265879 organism-based format Scientific Literature 10. ALA4266697 ADME Ratio of AUC in rat brain to plasma at 10 mg/kg, ip measured after 8 hrs Rattus norvegicus 4 ALA4265879 organism-based format Scientific Literature 11. ALA4266699 Functional Antidepressant like activity in Sprague-Dawley rat assessed as floating time at 3 mg/kg, ip administered at 24, 4 and 0.5 hrs prior to test by forced swimming test Rattus norvegicus 1 ALA4265879 organism-based format Scientific Literature 12. ALA4266700 Functional Antidepressant like activity in Sprague-Dawley rat assessed as swimming time at 3 mg/kg, ip administered at 24, 4 and 0.5 hrs prior to test by forced swimming test Rattus norvegicus 1 ALA4265879 organism-based format Scientific Literature 13. ALA4266701 Functional Antidepressant like activity in Sprague-Dawley rat assessed as climbing time at 3 mg/kg, ip administered at 24, 4 and 0.5 hrs prior to test by forced swimming test Rattus norvegicus 1 ALA4265879 organism-based format Scientific Literature