# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4271650 | F | Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
2. | ALA4271651 | F | Agonist activity at human beta1 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
3. | ALA4271652 | F | Agonist activity at human beta3 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
4. | ALA4271653 | B | Selectivity ratio of pEC50 for human beta2 adrenergic receptor expressed in HEK293 cells to pEC50 for human beta1 adrenergic receptor expressed in HEK293 cells | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
5. | ALA4271654 | F | Intrinsic activity at human beta2 adrenergic receptor in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay relative to isoprenaline | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
6. | ALA4271655 | F | Reduction in histamine-induced muscle contractions in Dunkin-Hartley guinea pig tracheal smooth muscle ring by measuring muscle tone | Cavia porcellus | 4 | tissue-based format | Scientific Literature | ||
7. | ALA4271656 | F | Reduction in histamine-induced muscle contractions in Dunkin-Hartley guinea pig tracheal smooth muscle ring by measuring muscle tone relative to control | Cavia porcellus | 4 | tissue-based format | Scientific Literature | ||
8. | ALA4271657 | F | Intrinsic activity at Dunkin-Hartley guinea pig tracheal smooth muscle ring assessed as reduction in histamine-induced muscle contractions by measuring muscle tone relative to isoprenaline | Cavia porcellus | 3 | tissue-based format | Scientific Literature |