| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4270311 | B | Displacement of [3-125I-Tyr11]-SRIF-14 or [3-125I-Tyr11]-SRIF-28 from human SSR5 expressed in CHOK1 cell membranes at 10 uM relative to control | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 2. | ALA4270312 | B | Displacement of [3-125I-Tyr11]-SRIF-14 or [3-125I-Tyr11]-SRIF-28 from human SSR5 expressed in CHOK1 cell membranes | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 3. | ALA4270313 | A | Metabolic stability in human liver microsomes at 1 uM after 30 mins | Homo sapiens | 29 | microsome format | Scientific Literature | ||
| 4. | ALA4270316 | A | Metabolic stability in rhesus monkey liver microsomes at 1 uM after 30 mins | Macaca mulatta | 29 | microsome format | Scientific Literature | ||
| 5. | ALA4270322 | F | Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins followed by forskolin addition measured after 1 hr by LANCE assay | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 6. | ALA4270323 | F | Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation at 8.3 mM preincubated for 15 mins followed by forskolin addition measured after 1 hr by LANCE assay relative to control | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 7. | ALA4270324 | F | Antagonist activity at mouse SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins followed by forskolin addition measured after 1 hr by LANCE assay | Mus musculus | 29 | cell-based format | Scientific Literature | ||
| 8. | ALA4270325 | F | Antagonist activity at mouse SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation at 8.3 mM preincubated for 15 mins followed by forskolin addition measured after 1 hr by LANCE assay relative to control | Mus musculus | 28 | cell-based format | Scientific Literature |
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