# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4257109 | B | Inhibition of rat NHE3 expressed in OK cells assessed as reduction in Na+ dependent H+ antiport in presence of NHE1 inhibitor EIPA by BCECF-AM dye based fluorescence assay | Rattus norvegicus | 182 | cell-based format | Patent Bioactivity Data | ||
2. | ALA4257111 | F | In vivo inhibition of NHE3 in Sprague-Dawley rat assessed as inhibition of sodium absorption from intestinal lumen by measuring urinary sodium concentration at 10 mg/kg, po via gavage measured after 16 hrs relative to control | Rattus norvegicus | 126 | organism-based format | Patent Bioactivity Data | ||
3. | ALA4257114 | F | In vivo inhibition of NHE3 in Sprague-Dawley rat assessed as urinary potassium concentration at 10 mg/kg, po via gavage measured after 16 hrs relative to control | Rattus norvegicus | 124 | organism-based format | Patent Bioactivity Data |