# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4260538 | B | Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis | Homo sapiens | 39 | single protein format | Scientific Literature | ||
2. | ALA4260540 | B | Inhibition of mouse GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis | Mus musculus | 1 | single protein format | Scientific Literature | ||
3. | ALA4260541 | B | Inhibition of rat GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
4. | ALA4260542 | A | Metabolic stability of human liver microsomes assessed as parent compound remaining at 0.1 uM after 60 mins in presence of NADPH by LC/MS/MS analysis | Homo sapiens | 13 | microsome format | Scientific Literature | ||
5. | ALA4260543 | A | Metabolic stability of rat liver microsomes assessed as parent compound remaining at 0.1 uM after 60 mins in presence of NADPH by LC/MS/MS analysis | Rattus norvegicus | 13 | microsome format | Scientific Literature | ||
6. | ALA4260544 | A | Metabolic stability of mouse liver microsomes assessed as parent compound remaining at 0.1 uM after 60 mins in presence of NADPH by LC/MS/MS analysis | Mus musculus | 13 | microsome format | Scientific Literature | ||
7. | ALA4260545 | A | Inhibition of CYP1A2 in human liver microsomes at 10 uM after 20 mins in presence of NADPH by LC/MS/MS analysis relative to control | Homo sapiens | 13 | microsome format | Scientific Literature | ||
8. | ALA4260546 | A | Inhibition of CYP2D6 in human liver microsomes at 10 uM after 20 mins in presence of NADPH by LC/MS/MS analysis relative to control | Homo sapiens | 13 | microsome format | Scientific Literature | ||
9. | ALA4260547 | A | Inhibition of CYP3A4 in human liver microsomes at 10 uM after 20 mins in presence of NADPH by LC/MS/MS analysis relative to control | Homo sapiens | 13 | microsome format | Scientific Literature | ||
10. | ALA4260548 | A | Inhibition of CYP2C9 in human liver microsomes at 10 uM after 20 mins in presence of NADPH by LC/MS/MS analysis relative to control | Homo sapiens | 13 | microsome format | Scientific Literature | ||
11. | ALA4260549 | A | Inhibition of CYP2C19 in human liver microsomes at 10 uM after 40 mins in presence of NADPH by LC/MS/MS analysis relative to control | Homo sapiens | 13 | microsome format | Scientific Literature | ||
12. | ALA4260550 | A | Clearance in C57/BL6 mouse at 3 mg/kg, iv | Mus musculus | 2 | organism-based format | Scientific Literature | ||
13. | ALA4260551 | A | Volume of distribution in C57/BL6 mouse at 3 mg/kg, iv | Mus musculus | 2 | organism-based format | Scientific Literature | ||
14. | ALA4260552 | A | Half life in C57/BL6 mouse at 3 mg/kg, iv | Mus musculus | 2 | organism-based format | Scientific Literature | ||
15. | ALA4260553 | A | Cmax in C57/BL6 mouse at 30 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
16. | ALA4260554 | A | AUC (0 to 24 hrs) in C57/BL6 mouse at 30 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
17. | ALA4260555 | A | Tmax in C57/BL6 mouse at 30 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
18. | ALA4260556 | A | Half life in C57/BL6 mouse at 30 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
19. | ALA4260557 | A | Oral bioavailability in C57/BL6 mouse at 30 mg/kg | Mus musculus | 2 | organism-based format | Scientific Literature | ||
20. | ALA4260558 | A | Ratio of drug uptake in lung to plasma of C57/BL6 mouse at 3 mg/kg, iv or 30 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature |