| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4276233 | B | Inhibition of recombinant His10-tagged ZZ-HCV3C-BRM ATPase-SnAC (636 to 1331 residues) (unknown origin) expressed in insect sf9 cells preincubated for 5 mins followed by pCMV-dR8.91 plasmid and ATP addition measured after 60 mins by ADP-Glo assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 2. | ALA4276234 | B | Inhibition of recombinant His6-tagged BRG1 ATPase-SnAC (658 to 1361 residues) (unknown origin) expressed in insect sf9 cells preincubated for 5 mins followed by pCMV-dR8.91 plasmid and ATP addition measured after 60 mins by ADP-Glo assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 3. | ALA4276235 | B | Binding affinity to BRG1 ATPase-SnAC domain (unknown origin) expressed in insect sf9 cells assessed as change in melting temperature at 100 uM by DSF-assay (Rvb = 0 degreeC) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4276237 | B | Binding affinity to BRG1 ATPase-SnAC domain (unknown origin) expressed in insect sf9 cells assessed as change in melting temperature at 100 uM in presence of ADP by DSF-assay (Rvb = 0 degreeC) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4276238 | B | Binding affinity to N-terminal avi-tagged BRM ATPase-SnAC domain (unknown origin) in absence of ADP by SPR assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4276239 | B | Binding affinity to N-terminal avi-tagged BRM ATPase-SnAC domain (unknown origin) in presence of ADP by SPR assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4276240 | B | Binding affinity to His6-tagged BRG1 ATPase-SnAC (658 to 1361 residues) (unknown origin) expressed in insect sf9 cells by ITC method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4276241 | P | Thermodynamic solubility of the compound at 1 mg/ml pH 1 after 16 to 24 hrs by shake-flask method | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 9. | ALA4276245 | P | Thermodynamic solubility of the compound at 1 mg/ml pH 6.8 after 16 to 24 hrs by shake-flask method | 4 | small-molecule physicochemical format | Scientific Literature | |||
| 10. | ALA4276253 | B | Inhibition of full length BRM ATPase (1 to 1572 residues) (unknown origin) expressed in insect sf9 cells preincubated for 5 mins followed by pCMV-dR8.91 plasmid and ATP addition measured after 60 mins by ADP-Glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4276259 | B | Inhibition of recombinant His10-tagged ZZ-HCV3C-BRM ATPase-SnAC (636 to 1331 residues) (unknown origin) expressed in insect sf9 cells preincubated for 5 mins followed by pCMV-dR8.91 and 10 times ATP addition measured after 60 mins by ADP-Glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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