| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4275697 | F | Antiproliferative activity against human BxPC3 cells after 24 hrs by MTT assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
| 2. | ALA4275698 | F | Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
| 3. | ALA4275699 | F | Antiproliferative activity against human PC3 cells after 24 hrs by MTT assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
| 4. | ALA4275700 | B | Displacement of fluormone VDR red from human full-length VDR at 1 uM after 4 hrs by fluorescence polarization assay | Homo sapiens | 40 | single protein format | Scientific Literature | ||
| 5. | ALA4275701 | B | Displacement of fluormone VDR red from human full-length VDR after 4 hrs by fluorescence polarization assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 6. | ALA4275702 | B | Transactivation of recombinant human VDR/RXRalpha expressed in HEK293 cells after 24 hrs by Dual-luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA4275703 | B | Binding affinity to VDR in scrambled siRNA-transfected human MCF7 cells assessed as cell growth inhibition by measuring reduction in BrdU incorporation after 16 hrs by ELISA | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA4275704 | F | Cell cycle arrest in human MCF7 cells expressing scrambled siRNA assessed as accumulation at G0/G1 phase at 1 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 49.28%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 9. | ALA4275705 | F | Antiproliferative activity against human MCF7 cells expressing VDR siRNA assessed as reduction in BrdU incorporation after 16 hrs by ELISA | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA4275706 | F | Cell cycle arrest in human MCF7 cells expressing scrambled siRNA assessed as accumulation at G2/M phase at 1 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 19.6%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 11. | ALA4275707 | F | Cell cycle arrest in human MCF7 cells expressing scrambled siRNA assessed as accumulation at S phase at 1 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 29.79%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 12. | ALA4275708 | F | Cell cycle arrest in human MCF7 cells expressing VDR siRNA assessed as accumulation at G0/G1 phase at 1 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 49.17%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 13. | ALA4275709 | F | Cell cycle arrest in human MCF7 cells expressing VDR siRNA assessed as accumulation at G2/M phase at 1 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 17.57%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 14. | ALA4275710 | F | Cell cycle arrest in human MCF7 cells expressing VDR siRNA assessed as accumulation at S phase at 1 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 32%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 15. | ALA4275711 | F | Induction of apoptosis in human MCF7 cells expressing scrambled siRNA assessed as live cells at 1 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry (Rvb = 97.93%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 16. | ALA4275712 | F | Induction of apoptosis in human MCF7 cells expressing scrambled siRNA assessed as early apoptotic cells at 1 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry (Rvb = 0.93%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 17. | ALA4275713 | F | Induction of apoptosis in human MCF7 cells expressing scrambled siRNA assessed as late apoptotic cells at 1 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry (Rvb = 0.98%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 18. | ALA4275714 | F | Induction of apoptosis in human MCF7 cells expressing scrambled siRNA assessed as necrotic cells at 1 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry (Rvb = 0.16%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 19. | ALA4275715 | F | Induction of apoptosis in human MCF7 cells expressing VDR siRNA assessed as live cells at 1 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry (Rvb = 98.35%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 20. | ALA4275716 | F | Induction of apoptosis in human MCF7 cells expressing VDR siRNA assessed as early apoptotic cells at 1 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry (Rvb = 0.49%) | Homo sapiens | 7 | cell-based format | Scientific Literature |
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