| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4262458 | B | Binding affinity to recombinant Mycobacterium tuberculosis Rv1284 expressed in Escherichia coli BL21-Al cells assessed as change in melting temperature by SYPRO Orange dye based differential scanning fluorimetric method | Mycobacterium tuberculosis | 15 | ALA4261513 | cell-based format | Scientific Literature | |
| 2. | ALA4262459 | B | Inhibition of recombinant Mycobacterium tuberculosis Rv1284 expressed in Escherichia coli BL21-Al cells assessed as enzyme residual activity at 25 uM measured for 10 secs by m-cresol purple staining based stopped-flow CO2 hydration assay relative to control | Mycobacterium tuberculosis | 15 | ALA4261513 | cell-based format | Scientific Literature | |
| 3. | ALA4262460 | B | Inhibition of recombinant Mycobacterium tuberculosis N-terminal Hi-tagged Rv3588c expressed in Escherichia coli BL21-Al cells assessed as enzyme residual activity at 25 uM measured for 10 secs by m-cresol purple staining based stopped-flow CO2 hydration assay relative to control | Mycobacterium tuberculosis | 15 | ALA4261513 | cell-based format | Scientific Literature | |
| 4. | ALA4705376 | F | Suppression of rotenone-induced ATP depletion in human HepG2 cells assessed as rescue of ATP level at 5 uM incubated for 2 hrs by Celltiter-Glo assay relative to control | Homo sapiens | 9 | ALA4699639 | cell-based format | Scientific Literature | |
| 5. | ALA4705377 | F | Suppression of rotenone-induced ATP depletion in human HepG2 cells assessed as increase in rescue of ATP level at 1 uM incubated for 2 hrs by Celltiter-Glo assay | Homo sapiens | 24 | ALA4699639 | cell-based format | Scientific Literature | |
| 6. | ALA4705379 | A | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability at 25 uM incubated for 24 hrs by Celltiter-blue assay relative to control | Homo sapiens | 28 | ALA4699639 | cell-based format | Scientific Literature | |
| 7. | ALA4705380 | A | Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability at 25 uM incubated for 24 hrs by Celltiter-blue assay | Homo sapiens | 31 | ALA4699639 | cell-based format | Scientific Literature |
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