# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4271800 | B | Inhibition of recombinant Plasmodium vivax plasmepsin 5 expressed in High five insect cells using DABCYLRNKRTLAQKQ-E-EDANS as substrate measured after 120 mins by fluorescence assay | Plasmodium vivax | 24 | cell-based format | Scientific Literature | ||
2. | ALA4271801 | B | Inhibition of plasmepsin 5 in Plasmodium falciparum 3D7 co-expressing PfEMP3-GFP infected in human erythrocytes assessed as accumulation of uncleaved PfEMP3-GFP at 1 to 20 uM after 3 hrs by immunoblot analysis | Plasmodium falciparum 3D7 | 2 | cell-based format | Scientific Literature | ||
3. | ALA4271804 | F | Antiplasmodial activity against ring-stage Plasmodium falciparum 3D7 assessed as reduction in parasite viability after 72 hrs by LDH assay | Plasmodium falciparum | 26 | organism-based format | Scientific Literature | ||
4. | ALA4271805 | F | Cytotoxicity against human HepG2 cells after 48 hrs by CellTiter-Glo assay | Homo sapiens | 27 | cell-based format | Scientific Literature |