| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4256853 | Functional | Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins followed by 5-oxo-ETE addition measured after 1 min by fluorescence assay | Homo sapiens | 18 | ALA4251757 | assay format | Scientific Literature | |
| 2. | ALA4256858 | ADME | Tmax in cynomolgus monkey plasma at 15 mg/kg administered via oral gavage by RP-HPLC analysis | Macaca fascicularis | 2 | ALA4251757 | organism-based format | Scientific Literature | |
| 3. | ALA4256864 | ADME | Cmax in cynomolgus monkey plasma at 15 mg/kg administered via oral gavage by RP-HPLC analysis | Macaca fascicularis | 2 | ALA4251757 | organism-based format | Scientific Literature | |
| 4. | ALA4256870 | ADME | Half life in cynomolgus monkey plasma at 15 mg/kg administered via oral gavage by RP-HPLC analysis | Macaca fascicularis | 2 | ALA4251757 | organism-based format | Scientific Literature | |
| 5. | ALA4256876 | ADME | AUC (0 to 24 hrs) in cynomolgus monkey plasma at 15 mg/kg administered via oral gavage by RP-HPLC analysis | Macaca fascicularis | 2 | ALA4251757 | organism-based format | Scientific Literature | |
| 6. | ALA4256883 | ADME | Plasma concentration in cynomolgus monkey at 30 mg/kg administered via oral gavage after 24 hrs by chiral-HPLC analysis | Macaca fascicularis | 2 | ALA4251757 | organism-based format | Scientific Literature | |
| 7. | ALA4256885 | ADME | Drug metabolism in cynomolgus monkey plasma at 30 mg/kg administered via oral gavage assessed as metabolite (S)-5-(5-Chloro-2-((S)-1-hydroxy-6-phenylhexyl)-1-methyl-1Hindol-3-yl)-3-methyl-5-oxopentanoic acid formation after 24 hrs by chiral-HPLC analysis | Macaca fascicularis | 1 | ALA4251757 | organism-based format | Scientific Literature | |
| 8. | ALA4256888 | ADME | Drug level in cynomolgus monkey plasma treated with 30 mg/kg 5-(5-Chloro-1-methyl-2-(6-phenylhexyl)-1H-indol-3-yl)-3-methyl-5-oxopentanoic Acid administered via oral gavage assessed as compound formation after 12 hrs by RP-HPLC analysis | Macaca fascicularis | 4 | ALA4251757 | organism-based format | Scientific Literature |
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