# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4267704 | F | Antiproliferative activity against mouse J774A.1 cells assessed as change in cell proliferation at 100 uM after 72 hrs by crystal violet staining based assay relative to control | Mus musculus | 20 | ALA4265921 | cell-based format | Scientific Literature | |
2. | ALA4267705 | F | Antiproliferative activity against mouse RAW264.7 cells assessed as change in cell proliferation at 100 uM after 72 hrs by crystal violet staining based assay relative to control | Mus musculus | 20 | ALA4265921 | cell-based format | Scientific Literature | |
3. | ALA4267706 | F | Antiproliferative activity against human MG63 cells assessed as change in cell proliferation at 100 uM after 72 hrs by crystal violet staining based assay relative to control | Homo sapiens | 20 | ALA4265921 | cell-based format | Scientific Literature | |
4. | ALA4267707 | F | Antiproliferative activity against human PC3 cells assessed as change in cell proliferation at 100 uM after 72 hrs by crystal violet staining based assay relative to control | Homo sapiens | 20 | ALA4265921 | cell-based format | Scientific Literature | |
5. | ALA4267708 | F | Antiproliferative activity against mouse J774A.1 cells assessed as reduction in cell proliferation at 500 uM after 72 hrs by crystal violet staining based assay | Mus musculus | 16 | ALA4265921 | cell-based format | Scientific Literature | |
6. | ALA4267709 | F | Antiproliferative activity against mouse RAW264.7 cells assessed as reduction in cell proliferation at 500 uM after 72 hrs by crystal violet staining based assay | Mus musculus | 16 | ALA4265921 | cell-based format | Scientific Literature | |
7. | ALA4267710 | F | Antiproliferative activity against human MG63 cells assessed as reduction in cell proliferation at 500 uM after 72 hrs by crystal violet staining based assay | Homo sapiens | 19 | ALA4265921 | cell-based format | Scientific Literature | |
8. | ALA4267711 | F | Antiproliferative activity against human PC3 cells assessed as reduction in cell proliferation at 500 uM after 72 hrs by crystal violet staining based assay | Homo sapiens | 19 | ALA4265921 | cell-based format | Scientific Literature | |
9. | ALA4267720 | B | Inhibition of recombinant human C-terminal His6-tagged FPPS expressed in Escherichia coli BL21 at 100 uM using DMAPP and IPP as substrates pretreated for 15 mins followed by substrates addition and measured after 1 hr by colorimetric method relative to control | Homo sapiens | 19 | ALA4265921 | assay format | Scientific Literature | |
10. | ALA4267721 | B | Inhibition of recombinant human C-terminal His6-tagged GGPPS expressed in Escherichia coli BL21 at 100 uM using IPP and FPP as substrates pretreated for 15 mins followed by substrates addition and measured after 1 hr by colorimetric method relative to control | Homo sapiens | 21 | ALA4265921 | assay format | Scientific Literature | |
11. | ALA4267722 | B | Inhibition of recombinant human C-terminal His6-tagged FPPS expressed in Escherichia coli BL21 at 1 to 10 uM using DMAPP and IPP as substrates pretreated for 15 mins followed by substrates addition and measured after 1 hr by colorimetric method relative to control | Homo sapiens | 19 | ALA4265921 | assay format | Scientific Literature | |
12. | ALA4267723 | B | Inhibition of recombinant human C-terminal His6-tagged GGPPS expressed in Escherichia coli BL21 at 1 to 10 uM using IPP and FPP as substrates pretreated for 15 mins followed by substrates addition and measured after 1 hr by colorimetric method relative to control | Homo sapiens | 19 | ALA4265921 | assay format | Scientific Literature | |
13. | ALA4267726 | B | Binding affinity to hydroxyapatite at 100 uM using sodium salt form of compound after 5 mins by ESI/MS analysis | 5 | ALA4265921 | assay format | Scientific Literature |