# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4261234 | B | Inhibition of human His6-tagged NEU1 expressed in HEK293 cells using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition and measured after 30 mins by fluorescence assay | Homo sapiens | 46 | cell-based format | Scientific Literature | ||
2. | ALA4261235 | B | Inhibition of N-terminal MBP-fused human NEU2 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition and measured after 30 mins by fluorescence assay | Homo sapiens | 46 | assay format | Scientific Literature | ||
3. | ALA4261236 | B | Inhibition of N-terminal MBP-fused human NEU3 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition and measured after 30 mins by fluorescence assay | Homo sapiens | 46 | assay format | Scientific Literature | ||
4. | ALA4261237 | B | Inhibition of MBP-fused human NEU4 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition and measured after 30 mins by fluorescence assay | Homo sapiens | 46 | assay format | Scientific Literature | ||
5. | ALA4261238 | B | Competitive inhibition of human His6-tagged NEU1 expressed in HEK293 cells using 4MU-NANA as substrate preincubated with substrate for 15 mins and measured every min for 30 mins by Lineweaver-Burk plot analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
6. | ALA4261240 | B | Competitive inhibition of N-terminal MBP-fused human NEU2 expressed in Escherichia coli using 4MU-NANA as substrate preincubated with substrate for 15 mins and measured every min for 30 mins by Lineweaver-Burk plot analysis | Homo sapiens | 5 | assay format | Scientific Literature | ||
7. | ALA4261250 | B | Selectivity index, ratio of IC50 for inhibition of MBP-fused human NEU4 expressed in Escherichia coli to IC50 for inhibition of human His6-tagged NEU1 expressed in HEK293 cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
8. | ALA4418863 | B | Inhibition of His6-tagged human neuraminidase-1 expressed in HEK293 cells pre-incubated for 15 mins before 4MU-NANA substrate addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 71 | cell-based format | Patent Bioactivity Data | ||
9. | ALA4418864 | B | Inhibition of N-terminal MBP tagged human neuraminidase-2 expressed in Escherichia coli pre-incubated for 15 mins before 4MU-NANA substrate addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 67 | assay format | Patent Bioactivity Data | ||
10. | ALA4418865 | B | Inhibition of N-terminal MBP tagged human neuraminidase-3 expressed in Escherichia coli pre-incubated for 15 mins before 4MU-NANA substrate addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 67 | assay format | Patent Bioactivity Data | ||
11. | ALA4418866 | B | Inhibition of N-terminal GST tagged human neuraminidase-4 expressed in Escherichia coli pre-incubated for 15 mins before 4MU-NANA substrate addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 67 | assay format | Patent Bioactivity Data | ||
12. | ALA4418875 | B | Selectivity index, ratio of IC50 for inhibition of N-terminal MBP tagged human neuraminidase-2 expressed in Escherichia coli to IC50 for inhibition of His6-tagged human neuraminidase-1 expressed in HEK293 cells | Homo sapiens | 29 | cell-based format | Patent Bioactivity Data | ||
13. | ALA4418876 | B | Selectivity index, ratio of IC50 for inhibition of N-terminal MBP tagged human neuraminidase-3 expressed in Escherichia coli to IC50 for inhibition of His6-tagged human neuraminidase-1 expressed in HEK293 cells | Homo sapiens | 29 | cell-based format | Patent Bioactivity Data | ||
14. | ALA4418877 | B | Selectivity index, ratio of IC50 for inhibition of N-terminal GST tagged human neuraminidase-4 expressed in Escherichia coli to IC50 for inhibition of His6-tagged human neuraminidase-1 expressed in HEK293 cells | Homo sapiens | 28 | cell-based format | Patent Bioactivity Data | ||
15. | ALA4418880 | B | Inhibition of N-terminal MBP tagged human neuraminidase-2 expressed in Escherichia coli pre-incubated for 15 mins before 4MU-NANA substrate addition and measured every 30 secs for 30 mins by fluorescence based assay | Homo sapiens | 8 | assay format | Patent Bioactivity Data | ||
16. | ALA4418881 | B | Inhibition of N-terminal MBP tagged human neuraminidase-3 expressed in Escherichia coli pre-incubated for 15 mins before 4MU-NANA substrate addition and measured every 30 secs for 30 mins by fluorescence based assay | Homo sapiens | 8 | assay format | Patent Bioactivity Data | ||
17. | ALA4418882 | B | Inhibition of N-terminal GST tagged human neuraminidase-4 expressed in Escherichia coli pre-incubated for 15 mins before 4MU-NANA substrate addition and measured every 30 secs for 30 mins by fluorescence based assay | Homo sapiens | 8 | assay format | Patent Bioactivity Data |