| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4271806 | ADME | Displacement of DAUDA from recombinant human N-terminal His-tagged FABP3 expressed in Escherichia coli BL21(DE3) after 20 mins by fluorescence assay | Homo sapiens | 47 | ALA4270525 | assay format | Scientific Literature | |
| 2. | ALA4271807 | Binding | Displacement of DAUDA from recombinant human N-terminal His-tagged FABP5 expressed in Escherichia coli BL21(DE3) after 20 mins by fluorescence assay | Homo sapiens | 47 | ALA4270525 | assay format | Scientific Literature | |
| 3. | ALA4271808 | Binding | Displacement of ANS from recombinant human N-terminal His-tagged FABP7 expressed in Escherichia coli BL21(DE3) after 20 mins by fluorescence assay | Homo sapiens | 47 | ALA4270525 | assay format | Scientific Literature | |
| 4. | ALA4271809 | Functional | Antinociceptive activity in C57BL/6 mouse model of complete Freund's adjuvant-induced inflammatory pain assessed as increase in paw withdrawal latency at 40 mg/kg, ip measured after 90 mins by plantar test | Mus musculus | 8 | ALA4270525 | organism-based format | Scientific Literature | |
| 5. | ALA4271811 | Functional | Antinociceptive activity in FABP5 knock out C57BL/6 mouse model of complete Freund's adjuvant-induced inflammatory pain assessed as increase in paw withdrawal latency at 40 mg/kg, ip measured after 90 mins by plantar test | Mus musculus | 1 | ALA4270525 | organism-based format | Scientific Literature | |
| 6. | ALA4271813 | Binding | Displacement of NBD-stearate from recombinant human N-terminal His-tagged FABP5 expressed in Escherichia coli BL21(DE3) by fluorescence assay | Homo sapiens | 1 | ALA4270525 | assay format | Scientific Literature | |
| 7. | ALA4271814 | Binding | Displacement of NBD-stearate from recombinant human N-terminal His-tagged FABP7 expressed in Escherichia coli BL21(DE3) by fluorescence assay | Homo sapiens | 1 | ALA4270525 | assay format | Scientific Literature | |
| 8. | ALA4271815 | ADME | Displacement of NBD-stearate from recombinant human N-terminal His-tagged FABP3 expressed in Escherichia coli BL21(DE3) by fluorescence assay | Homo sapiens | 1 | ALA4270525 | assay format | Scientific Literature | |
| 9. | ALA4271816 | ADME | Half life in C57BL/6 mouse at 20 mg/kg, ip by LC-MS analysis | Mus musculus | 1 | ALA4270525 | organism-based format | Scientific Literature | |
| 10. | ALA4271817 | Physicochemical | Colloidal aggregation of the compound at 20 uM by dynamic light scattering method | 2 | ALA4270525 | small-molecule physicochemical format | Scientific Literature |
The page will load shortly, Thanks for your patience!