| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4268221 | B | Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by ion exchange filter paper method | Homo sapiens | 29 | ALA4265943 | single protein format | Scientific Literature | |
| 2. | ALA4268222 | B | Inhibition of HDAC1 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and measured for 1.5 hrs at 15 mins time interval by fluorescence assay | Homo sapiens | 23 | ALA4265943 | single protein format | Scientific Literature | |
| 3. | ALA4268223 | B | Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and measured for 1.5 hrs at 15 mins time interval by fluorescence assay | Homo sapiens | 23 | ALA4265943 | single protein format | Scientific Literature | |
| 4. | ALA4268233 | F | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay | Homo sapiens | 25 | ALA4265943 | cell-based format | Scientific Literature | |
| 5. | ALA4268234 | F | Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay | Homo sapiens | 25 | ALA4265943 | cell-based format | Scientific Literature | |
| 6. | ALA4268235 | F | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay | Homo sapiens | 25 | ALA4265943 | cell-based format | Scientific Literature | |
| 7. | ALA4268236 | F | Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay | Homo sapiens | 25 | ALA4265943 | cell-based format | Scientific Literature | |
| 8. | ALA4268237 | A | Antiproliferative activity against human AC10 cells after 72 hrs by MTT assay | Homo sapiens | 20 | ALA4265943 | cell-based format | Scientific Literature | |
| 9. | ALA4268238 | A | Antiproliferative activity against mouse TAMH cells after 72 hrs by MTT assay | Mus musculus | 20 | ALA4265943 | cell-based format | Scientific Literature | |
| 10. | ALA4268241 | T | Selectivity index, ratio of CC50 for human AC10 cells to IC50 for human MDA-MB-231 cells | Homo sapiens | 19 | ALA4265943 | assay format | Scientific Literature | |
| 11. | ALA4268242 | T | Selectivity index, ratio of CC50 for mouse TAMH cells to IC50 for human MDA-MB-231 cells | 19 | ALA4265943 | assay format | Scientific Literature | ||
| 12. | ALA4268243 | T | Selectivity index, ratio of CC50 for human AC10 cells to IC50 for human MCF7 cells | Homo sapiens | 19 | ALA4265943 | assay format | Scientific Literature | |
| 13. | ALA4268244 | T | Selectivity index, ratio of CC50 for mouse TAMH cells to IC50 for human MCF7 cells | 19 | ALA4265943 | assay format | Scientific Literature | ||
| 14. | ALA4268245 | T | Selectivity index, ratio of CC50 for human AC10 cells to IC50 for human PC3 cells | Homo sapiens | 19 | ALA4265943 | assay format | Scientific Literature | |
| 15. | ALA4268246 | T | Selectivity index, ratio of CC50 for mouse TAMH cells to IC50 for human PC3 cells | 19 | ALA4265943 | assay format | Scientific Literature | ||
| 16. | ALA4268269 | F | Induction of apoptosis in human PC3 cells assessed as live cells at 1.07 uM after 72 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 96.36%) | Homo sapiens | 1 | ALA4265943 | cell-based format | Scientific Literature | |
| 17. | ALA4268270 | F | Induction of apoptosis in human PC3 cells assessed as early apoptotic cells at 1.07 uM after 72 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 1.97%) | Homo sapiens | 1 | ALA4265943 | cell-based format | Scientific Literature | |
| 18. | ALA4268271 | F | Induction of apoptosis in human PC3 cells assessed as late apoptotic cells at 1.07 uM after 72 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 1.01%) | Homo sapiens | 1 | ALA4265943 | cell-based format | Scientific Literature | |
| 19. | ALA4268272 | F | Induction of apoptosis in human PC3 cells assessed as necrotic cells at 1.07 uM after 72 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 0.66%) | Homo sapiens | 1 | ALA4265943 | cell-based format | Scientific Literature | |
| 20. | ALA4268277 | F | Induction of apoptosis in human HCT116 cells assessed as live cells at 0.99 uM after 72 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 95.7%) | Homo sapiens | 1 | ALA4265943 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!