# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4254200 | Functional | Cytotoxicity activity against human U937 cells assessed as reduction in cell viability after 48 hrs by CCK-8 assay | Homo sapiens | 10 | ALA4251620 | cell-based format | Scientific Literature | |
2. | ALA4254202 | Functional | Induction of apoptosis in human U937 cells assessed as increase in caspase-3/7 activity at 3 uM after 6 hrs | Homo sapiens | 5 | ALA4251620 | cell-based format | Scientific Literature | |
3. | ALA4254203 | Functional | Cytotoxicity activity against human U937 cells assessed as cell viability at 1 uM after 48 hrs by CCK-8 assay | Homo sapiens | 18 | ALA4251620 | cell-based format | Scientific Literature | |
4. | ALA4254204 | Functional | Induction of apoptosis in human U937 cells assessed as viable cells at 3 uM after 48 hrs by muse Annexin V/dead cell reagent staining-based flow cytometric analysis (Rvb = 97.07%) | Homo sapiens | 5 | ALA4251620 | cell-based format | Scientific Literature | |
5. | ALA4254205 | Functional | Induction of apoptosis in human U937 cells assessed as early apoptotic cells at 3 uM after 48 hrs by muse Annexin V/dead cell reagent staining-based flow cytometric analysis (Rvb = 1.87%) | Homo sapiens | 5 | ALA4251620 | cell-based format | Scientific Literature | |
6. | ALA4254206 | Functional | Induction of apoptosis in human U937 cells assessed as late apoptotic cells at 3 uM after 48 hrs by muse Annexin V/dead cell reagent staining-based flow cytometric analysis (Rvb = 1%) | Homo sapiens | 5 | ALA4251620 | cell-based format | Scientific Literature | |
7. | ALA4254207 | Functional | Induction of apoptosis in human U937 cells assessed as necrotic cells at 3 uM after 48 hrs by muse Annexin V/dead cell reagent staining-based flow cytometric analysis (Rvb = 0.06%) | Homo sapiens | 5 | ALA4251620 | cell-based format | Scientific Literature | |
8. | ALA4254208 | Functional | Induction of apoptosis in human U937 cells assessed as viable cells at 10 uM after 48 hrs by muse Annexin V/dead cell reagent staining-based flow cytometric analysis (Rvb = 97.07%) | Homo sapiens | 5 | ALA4251620 | cell-based format | Scientific Literature | |
9. | ALA4254209 | Functional | Induction of apoptosis in human U937 cells assessed as early apoptotic cells at 10 uM after 48 hrs by muse Annexin V/dead cell reagent staining-based flow cytometric analysis (Rvb = 1.87%) | Homo sapiens | 5 | ALA4251620 | cell-based format | Scientific Literature | |
10. | ALA4254210 | Functional | Induction of apoptosis in human U937 cells assessed as late apoptotic cells at 10 uM after 48 hrs by muse Annexin V/dead cell reagent staining-based flow cytometric analysis (Rvb = 1%) | Homo sapiens | 5 | ALA4251620 | cell-based format | Scientific Literature | |
11. | ALA4254211 | Functional | Induction of apoptosis in human U937 cells assessed as necrotic cells at 10 uM after 48 hrs by muse Annexin V/dead cell reagent staining-based flow cytometric analysis (Rvb = 0.06%) | Homo sapiens | 5 | ALA4251620 | cell-based format | Scientific Literature | |
12. | ALA4254212 | Functional | Cytotoxicity against human Raji cells assessed as reduction in cell viability after 48 hrs by CCK-8 assay | Homo sapiens | 2 | ALA4251620 | cell-based format | Scientific Literature | |
13. | ALA4254213 | Functional | Cytotoxicity activity against human JeKo1 cells assessed as reduction in cell viability after 48 hrs by CCK-8 assay | Homo sapiens | 2 | ALA4251620 | cell-based format | Scientific Literature | |
14. | ALA4254214 | Functional | Induction of apoptosis in human U937 cells at 10 uM after 48 hrs by muse Annexin V/dead cell reagent staining-based flow cytometric analysis (Rvb = 2.95%) | Homo sapiens | 2 | ALA4251620 | cell-based format | Scientific Literature | |
15. | ALA4254215 | Functional | Induction of apoptosis in human Raji cells at 10 uM after 48 hrs by muse Annexin V/dead cell reagent staining-based flow cytometric analysis (Rvb = 9.58%) | Homo sapiens | 2 | ALA4251620 | cell-based format | Scientific Literature | |
16. | ALA4254216 | Functional | Induction of apoptosis in human JeKo1 cells at 10 uM after 48 hrs by muse Annexin V/dead cell reagent staining-based flow cytometric analysis (Rvb = 5.21%) | Homo sapiens | 2 | ALA4251620 | cell-based format | Scientific Literature |