# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4253045 | B | Inhibition of biotin-labeled MBP (85 to 99 residues) binding to HLA class 2 DRB1*1501 mutant allele after 2 hrs by TMB + substrate-chromogen based assay | Homo sapiens | 3 | ALA4251586 | single protein format | Scientific Literature | |
2. | ALA4253046 | B | Inhibition of biotin-labeled MBP (85 to 99 residues) binding to HLA class 2 DRB1*0101 mutant allele after 2 hrs by TMB + substrate-chromogen based assay | Homo sapiens | 3 | ALA4251586 | single protein format | Scientific Literature | |
3. | ALA4253049 | A | Drug localization in cytoplasm of human Jurkat T cells at 2 uM after 10 mins by Hoechst/Mitotracker Red staining-based inverted fluorescence microscopy | Homo sapiens | 1 | ALA4251586 | subcellular format | Scientific Literature | |
4. | ALA4253050 | A | Drug localization in nucleus of human Jurkat T cells at 2 uM after 20 to 30 mins by Hoechst/Mitotracker Red staining-based inverted fluorescence microscopy | Homo sapiens | 1 | ALA4251586 | subcellular format | Scientific Literature | |
5. | ALA4253051 | P | Aqueous solubility of the compound in water | 1 | ALA4251586 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4253055 | F | Induction of apoptosis in human Jurkat T cells assessed as downregulation of Bcl2 expression at 10 uM after 48 hrs by Western blot analysis | Homo sapiens | 3 | ALA4251586 | cell-based format | Scientific Literature | |
7. | ALA4253056 | A | Drug localization in cytoplasm of human Jurkat T cells at 2 uM after 10 mins pre-treated with cisplatin for 30 mins before compound addition by Hoechst/Mitotracker Red staining-based inverted fluorescence microscopy | Homo sapiens | 1 | ALA4251586 | subcellular format | Scientific Literature | |
8. | ALA4253057 | A | Drug localization in nucleus of human Jurkat T cells at 2 uM after 20 to 30 mins pre-treated with cisplatin for 30 mins before compound addition by Hoechst/Mitotracker Red staining-based inverted fluorescence microscopy | Homo sapiens | 1 | ALA4251586 | subcellular format | Scientific Literature |