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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4258932 B Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21insect cells using poly (4:1 Glu, Tyr) as substrate measured after 1 hr by ELISA Homo sapiens 11 ALA4257496 cell-based format Scientific Literature 2. ALA4258936 B Inhibition of EGFR (unknown origin) at 100 nM using poly (4:1 Glu, Tyr) as substrate measured after 1 hr by ELISA Homo sapiens 3 ALA4257496 single protein format Scientific Literature 3. ALA4258937 B Inhibition of ErbB4 (unknown origin) at 100 nM using poly (4:1 Glu, Tyr) as substrate measured after 1 hr by ELISA Homo sapiens 3 ALA4257496 single protein format Scientific Literature 4. ALA4258938 B Inhibition of ErbB2 (unknown origin) at 100 nM using poly (4:1 Glu, Tyr) as substrate measured after 1 hr by ELISA relative to control Homo sapiens 3 ALA4257496 single protein format Scientific Literature 5. ALA4258939 B Inhibition of ITK (unknown origin) at 100 nM using poly (4:1 Glu, Tyr) as substrate measured after 1 hr by ELISA relative to control Homo sapiens 3 ALA4257496 single protein format Scientific Literature 6. ALA4258941 B Inhibition of EGFR (unknown origin) using poly (4:1 Glu, Tyr) as substrate measured after 1 hr by ELISA Homo sapiens 1 ALA4257496 single protein format Scientific Literature 7. ALA4258942 B Selectivity ratio of IC50 for EGFR (unknown origin) to IC50 for recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21insect cells Homo sapiens 1 ALA4257496 cell-based format Scientific Literature 8. ALA4427027 B Inhibition of wild type EGFR kinase domain (unknown origin) expressed using baculovirus expression system incubated for 1 hr using Poly(Glu,Tyr) 4:1 by ELISA method Homo sapiens 11 ALA4425144 assay format Scientific Literature 9. ALA4427028 B Inhibition of EGFR kinase domain L858R/T790M mutant (unknown origin) expressed using baculovirus expression system incubated for 1 hr using Poly(Glu,Tyr) 4:1 by ELISA method Homo sapiens 11 ALA4425144 assay format Scientific Literature 10. ALA4427029 B Selectivity index, ratio of IC50 for wild type EGFR kinase domain (unknown origin) to IC50 for EGFR kinase domain L858R/T790M mutant (unknown origin) Homo sapiens 11 ALA4425144 assay format Scientific Literature 11. ALA4427030 F Antiproliferative activity against human A431 cells incubated for 72 hrs by SRB assay Homo sapiens 11 ALA4425144 cell-based format Scientific Literature 12. ALA4427031 F Antiproliferative activity against human NCI-H1975 cells incubated for 72 hrs by SRB assay Homo sapiens 11 ALA4425144 cell-based format Scientific Literature 13. ALA4427032 F Selectivity index, ratio of IC50 for human A431 cells to IC50 for human NCI-H1975 cells Homo sapiens 11 ALA4425144 assay format Scientific Literature 14. ALA4427037 P Dissociation constant, pKa of the compound by Sirius T3 based assay 10 ALA4425144 small-molecule physicochemical format Scientific Literature 15. ALA4427038 P Thermodynamic solubility of the compound in 0.1M PBS buffer at pH 7.4 by UV-visible spectrophotometry 10 ALA4425144 small-molecule physicochemical format Scientific Literature 16. ALA4427039 P Glutathione reactivity in 0.1 M PBS buffer at pH 7.4 at 1 mM in presence of 10 mM glutathione and 10% dimethylacetamide at 37 degC incubated for 24 hrs by HRMS method 1 ALA4425144 small-molecule physicochemical format Scientific Literature 17. ALA4427040 B Inhibition of human ASK2 expressed in mammalian system assessed as remaining enzyme activity at 1000 nM relative to untreated control Homo sapiens 1 ALA4425144 assay format Scientific Literature 18. ALA4427041 B Inhibition of human CAMK1 expressed in bacterial system assessed as remaining enzyme activity at 1000 nM relative to untreated control Homo sapiens 1 ALA4425144 assay format Scientific Literature 19. ALA4427042 B Inhibition of human ERBB2 expressed in mammalian system assessed as remaining enzyme activity at 1000 nM relative to untreated control Homo sapiens 1 ALA4425144 assay format Scientific Literature 20. ALA4427043 B Inhibition of human ERBB4 expressed in bacterial system assessed as remaining enzyme activity at 1000 nM relative to untreated control Homo sapiens 1 ALA4425144 assay format Scientific Literature