# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4273265 | F | Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assay | Mus musculus | 16 | ALA4270564 | assay format | Scientific Literature | |
2. | ALA4273266 | B | Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assay | Mus musculus | 16 | ALA4270564 | single protein format | Scientific Literature | |
3. | ALA4273267 | B | Inhibition of Gli1 transcriptional activity in Smo-/- mouse embroyonic fibroblasts up to 20 uM after 24 hrs by renilla luciferase reporter gene assay | Mus musculus | 4 | ALA4270564 | single protein format | Scientific Literature | |
4. | ALA4273269 | F | Antagonist activity at smo in SuFu-/- mouse embroyonic fibroblasts assessed as downregulation of Gli1 mRNA levels after 48 hrs by qRT-PCR method | Mus musculus | 2 | ALA4270564 | assay format | Scientific Literature | |
5. | ALA4273271 | F | Growth inhibition of mouse Ptch+/- medulloblastoma cells at 0.125 uM after 72 hrs relative to control | Mus musculus | 5 | ALA4270564 | cell-based format | Scientific Literature | |
6. | ALA4273272 | F | Growth inhibition of mouse Ptch+/- medulloblastoma cells at 0.25 uM after 72 hrs relative to control | Mus musculus | 5 | ALA4270564 | cell-based format | Scientific Literature | |
7. | ALA4273273 | F | Growth inhibition of mouse Ptch+/- medulloblastoma cells at 0.5 uM after 72 hrs relative to control | Mus musculus | 5 | ALA4270564 | cell-based format | Scientific Literature | |
8. | ALA4273274 | F | Growth inhibition of mouse Ptch+/- medulloblastoma cells at 1 uM after 72 hrs relative to control | Mus musculus | 5 | ALA4270564 | cell-based format | Scientific Literature | |
9. | ALA4273275 | F | Growth inhibition of mouse Ptch+/- medulloblastoma cells at 2 uM after 72 hrs relative to control | Mus musculus | 5 | ALA4270564 | cell-based format | Scientific Literature | |
10. | ALA4273276 | F | Synergistic growth inhibition of mouse Ptch+/- medulloblastoma cells at 0.125 uM after 72 hrs in presence of Gli inhibitor GlaB | Mus musculus | 2 | ALA4270564 | cell-based format | Scientific Literature | |
11. | ALA4273277 | F | Synergistic growth inhibition of mouse Ptch+/- medulloblastoma cells at 0.25 uM after 72 hrs in presence of Gli inhibitor GlaB | Mus musculus | 2 | ALA4270564 | cell-based format | Scientific Literature | |
12. | ALA4273278 | F | Synergistic growth inhibition of mouse Ptch+/- medulloblastoma cells at 0.5 uM after 72 hrs in presence of Gli inhibitor GlaB | Mus musculus | 2 | ALA4270564 | cell-based format | Scientific Literature | |
13. | ALA4273280 | F | Antagonist activity at smo in SuFu-/- mouse embroyonic fibroblasts assessed as downregulation of Gli2 mRNA levels after 48 hrs by qRT-PCR method | Mus musculus | 2 | ALA4270564 | assay format | Scientific Literature |