| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4271946 | B | Inhibition of PDK1 (unknown origin) assessed as reduction in PDC phosphorylation | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 2. | ALA4271950 | F | Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 3. | ALA4271951 | F | Cytotoxicity against human A375 cells assessed as decrease in cell viability after 72 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 4. | ALA4271952 | F | Cytotoxicity against human NCI-H1650 cells assessed as decrease in cell viability after 72 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 5. | ALA4271953 | A | Cytotoxicity against human BEAS2B cells assessed as decrease in cell viability after 72 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 6. | ALA4271954 | T | Selectivity index, ratio of IC50 for human BEAS2B cells to IC50 for human NCI-H1650 cells | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 7. | ALA4271955 | B | Inhibition of porcine heart PDK1 assessed as ATP consumption after 3 mins | Sus scrofa | 11 | assay format | Scientific Literature | ||
| 8. | ALA4271957 | A | Inhibition of ERK phosphorylation in human NCI-H1650 cells at 2 uM after 12 hrs by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA4271958 | F | Induction of apoptosis in human NCI-H1650 cells at 0.5 to 2 uM by Annexin V-FITC/PI staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4271963 | F | Induction of apoptosis in human NCI-H1650 cells assessed as viable cells at 0.5 uM after 12 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 93.5%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4271964 | F | Induction of apoptosis in human NCI-H1650 cells assessed as early apoptotic cells at 0.5 uM after 12 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 1.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4271965 | F | Induction of apoptosis in human NCI-H1650 cells assessed as late apoptotic cells at 0.5 uM after 12 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 3.5%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4271966 | F | Induction of apoptosis in human NCI-H1650 cells assessed as necrotic cells at 0.5 uM after 12 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 1.6%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4271967 | F | Induction of apoptosis in human NCI-H1650 cells assessed as viable cells at 1 uM after 12 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 93.5%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4271968 | F | Induction of apoptosis in human NCI-H1650 cells assessed as early apoptotic cells at 1 uM after 12 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 1.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4271969 | F | Induction of apoptosis in human NCI-H1650 cells assessed as late apoptotic cells at 1 uM after 12 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 3.5%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4271970 | F | Induction of apoptosis in human NCI-H1650 cells assessed as necrotic cells at 1 uM after 12 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 1.6%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4271971 | F | Induction of apoptosis in human NCI-H1650 cells assessed as viable cells at 2 uM after 12 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 93.5%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4271972 | F | Induction of apoptosis in human NCI-H1650 cells assessed as early apoptotic cells at 2 uM after 12 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 1.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4271973 | F | Induction of apoptosis in human NCI-H1650 cells assessed as late apoptotic cells at 2 uM after 12 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 3.5%) | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!