| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4271491 | B | Inhibition of recombinant human HSF1 expressed in Escherichia coli BL21 (DE3) assessed as reduction in HSF1 trimer-5-fluorescein labeled HSE interaction at 400 uM preincubated for 1 hr followed by DNA tracer addition and measured after 15 mins by competitive fluorescence polarization assay | Homo sapiens | 13 | ALA4270511 | assay format | Scientific Literature | |
| 2. | ALA4271493 | B | Inhibition of recombinant human HSF1 expressed in Escherichia coli BL21 (DE3) assessed as reduction in HSF1 trimer-5-fluorescein labeled HSE interaction preincubated for 1 hr followed by DNA tracer addition and measured after 15 mins by competitive fluorescence polarization assay | Homo sapiens | 2 | ALA4270511 | assay format | Scientific Literature | |
| 3. | ALA4271494 | B | Inhibition of recombinant human HSF1 expressed in Escherichia coli BL21 (DE3) assessed as reduction in HSF1 trimer-5-fluorescein labeled HSE interaction preincubated of protein with DNA tracer up to 24 hrs followed by compound addition and measured after 15 mins by fluorescence polarization assay | Homo sapiens | 1 | ALA4270511 | assay format | Scientific Literature | |
| 4. | ALA4271497 | B | Disruption of full length human HSF1 trimer structure at 20 uM after 30 mins by size-exclusion chromatographic method | Homo sapiens | 1 | ALA4270511 | single protein format | Scientific Literature | |
| 5. | ALA4271498 | B | Disruption of full length human HSF1 trimer structure at 20 uM after 30 mins by SDS-PAGE analysis | Homo sapiens | 1 | ALA4270511 | single protein format | Scientific Literature | |
| 6. | ALA4271499 | B | Disruption of full length human HSF1 trimer structure at 20 uM after 30 mins by Western blot analysis | Homo sapiens | 1 | ALA4270511 | single protein format | Scientific Literature |
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