Prodrug activation assessed as Escherichia coli beta-glucuronidase-mediated N2-((1r,4r)-4-aminocyclohexyl)-8-isopropyl-N4-(4-(pyridin-2-yl)benzyl)pyrazolo[1,5-a][1,3,5]triazine-2,4-diamine formation after 20 hrs in presence of human serum albumin by HPLC-HRMS analysis
Prodrug activation assessed as N2-((1r,4r)-4-aminocyclohexyl)-8-isopropyl-N4-(4-(pyridin-2-yl)benzyl)pyrazolo[1,5-a][1,3,5]triazine-2,4-diamine formation after 20 hrs in presence of human serum albumin by HPLC-HRMS analysis