| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4265322 | B | Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assay | Homo sapiens | 118 | single protein format | Scientific Literature | ||
| 2. | ALA4265323 | B | Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured after 1 hr by Alexofluor 488-conjugated secondary antibody and Hoechst 33342 staining based assay | Homo sapiens | 50 | cell-based format | Scientific Literature | ||
| 3. | ALA4265327 | B | Inhibition of human full length C-terminus His-tagged ARH3 expressed in Escherichia coli using Bt-NAD ribosylated PARP1 substrate after 30 mins by TR-FRET assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 4. | ALA4265328 | B | Inhibition of human PARP1 expressed in Escherichia coli using activated DNA as substrate after 60 mins by peroxy glow reagent A/B based assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 5. | ALA4265329 | T | Selectivity ratio of cytotoxicity for human HeLa cells to EC50 for human full length PARG | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 6. | ALA4265330 | A | Clearance in human liver microsomes | Homo sapiens | 20 | microsome format | Scientific Literature |
The page will load shortly, Thanks for your patience!