# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4268714 | F | Cytotoxicity against imatinib-sensitive human K562 cells assessed as decrease in cell viability after 24 hrs by XTT assay | Homo sapiens | 17 | ALA4265959 | cell-based format | Scientific Literature | |
2. | ALA4268715 | B | Inhibition of heme oxygenase 1 in Sprague-Dawley rat spleen microsomal fraction assessed as decrease in bilirubin formation using biliverdin reductase as substrate after 60 mins by spectrophotometric method | Rattus norvegicus | 20 | ALA4265959 | subcellular format | Scientific Literature | |
3. | ALA4268716 | F | Cytotoxicity against human K562R cells assessed as decrease in cell viability after 24 hrs by XTT assay | Homo sapiens | 17 | ALA4265959 | cell-based format | Scientific Literature | |
4. | ALA4268719 | B | Inhibition of BCR-ABL in human K562R cells assessed as decrease in CrKL phosphorylation at 10 uM by immuno blot analysis | Homo sapiens | 7 | ALA4265959 | cell-based format | Scientific Literature | |
5. | ALA4268720 | A | Cytotoxicity against human lymphocytes assessed as decrease in cell viability at 10 uM after 24 hrs by XTT assay | Homo sapiens | 5 | ALA4265959 | cell-based format | Scientific Literature | |
6. | ALA4268721 | F | Induction of apoptosis in human K562R cells assessed as viable cells at 10 uM by Annexin V staining-based flow cytometry (Rvb = 81.13%) | Homo sapiens | 6 | ALA4265959 | cell-based format | Scientific Literature | |
7. | ALA4268722 | F | Induction of apoptosis in human K562R cells assessed as early apoptotic cells at 10 uM by Annexin V staining-based flow cytometry (Rvb = 8.51%) | Homo sapiens | 6 | ALA4265959 | cell-based format | Scientific Literature | |
8. | ALA4268723 | F | Induction of apoptosis in human K562R cells assessed as late apoptotic cells at 10 uM by Annexin V staining-based flow cytometry (Rvb = 9.49%) | Homo sapiens | 6 | ALA4265959 | cell-based format | Scientific Literature | |
9. | ALA4268724 | F | Induction of apoptosis in human K562R cells assessed as necrotic cells at 10 uM by Annexin V staining-based flow cytometry (Rvb = 0.87%) | Homo sapiens | 6 | ALA4265959 | cell-based format | Scientific Literature | |
10. | ALA4268725 | B | Inhibition of heme oxygenase 1 in human K562R cell lysates assessed as decrease in bilirubin formation at 10 uM after 60 mins by spectrophotometric method | Homo sapiens | 5 | ALA4265959 | single protein format | Scientific Literature | |
11. | ALA4268726 | B | Inhibition of heme oxygenase 1 in human K562R cells assessed as decrease in HO-1 mRNA levels at 10 uM by qRT-PCR method | Homo sapiens | 3 | ALA4265959 | cell-based format | Scientific Literature | |
12. | ALA4268727 | F | Effect on heme oxygenase 2 mRNA levels in human K562R cells at 10 uM by qRT-PCR method | Homo sapiens | 2 | ALA4265959 | cell-based format | Scientific Literature | |
13. | ALA4268728 | F | Induction of ROS production in human K562R cells at 10 uM by DCFH-DA dye based spectrofluorometric method | Homo sapiens | 5 | ALA4265959 | cell-based format | Scientific Literature |