# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4252097 | Binding | Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as substrate measured over 6 mins by spectrophotometric method | Trypanosoma | 17 | ALA4251554 | assay format | Scientific Literature | |
2. | ALA4252098 | Functional | Growth inhibition of Trypanosoma brucei brucei Lister 427 assessed as reduction in ATP levels after 48 hrs by CellTiter-Glo assay | Trypanosoma brucei brucei | 11 | ALA4251554 | organism-based format | Scientific Literature | |
3. | ALA4252099 | Binding | Mixed type non-competitive inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 at 1 to 10 nM using varying levels of 1-ubiquinol as substrate measured over 6 mins by spectrophotometric metho | Trypanosoma | 1 | ALA4251554 | assay format | Scientific Literature | |
4. | ALA4252100 | ADME | Cytotoxicity against human HepG2 cells after 96 hrs by CCK8 assay | Homo sapiens | 11 | ALA4251554 | cell-based format | Scientific Literature | |
5. | ALA4252101 | Toxicity | Selectivity index, ratio of CC50 for human HepG2 cells to IC50 for growth inhibition of Trypanosoma brucei brucei Lister 427 | 3 | ALA4251554 | assay format | Scientific Literature | ||
6. | ALA5121453 | Functional | Antibacterial activity aginst Bacillus subtilis DSM 10 assessed as inhibition of bacterial growth incubated for overnight by serial dilution method | Bacillus subtilis | 13 | ALA5120760 | organism-based format | Scientific Literature | |
7. | ALA5121458 | Functional | Antifungal activity against Mucor hiemalis DSM 2656 assessed as inhibition of fungal growth incubated for overnight by serial dilution method | Mucor hiemalis | 12 | ALA5120760 | organism-based format | Scientific Literature | |
8. | ALA5121464 | Functional | Antibacterial activity against Staphylococcus aureus DSM 346 assessed as inhibition of bacterial growth incubated for overnight by serial dilution method | Staphylococcus aureus | 14 | ALA5120760 | organism-based format | Scientific Literature | |
9. | ALA5121465 | Functional | Cytotoxicity against mouse L929 cells assessed as inhibition of cell proliferation incubated for 5 days by MTT assay | Mus musculus | 13 | ALA5120760 | cell-based format | Scientific Literature | |
10. | ALA5121466 | Functional | Cytotoxicity against human KB 3-1 cells assessed as inhibition of cell proliferation incubated for 5 days by MTT assay | Homo sapiens | 13 | ALA5120760 | cell-based format | Scientific Literature | |
11. | ALA5121467 | Functional | Cytotoxicity against human PC-3 cells assessed as inhibition of cell proliferation incubated for 5 days by MTT assay | Homo sapiens | 6 | ALA5120760 | cell-based format | Scientific Literature | |
12. | ALA5121468 | Functional | Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 5 days by MTT assay | Homo sapiens | 6 | ALA5120760 | cell-based format | Scientific Literature | |
13. | ALA5121469 | Functional | Cytotoxicity against human SK-OV-3 cells assessed as inhibition of cell proliferation incubated for 5 days by MTT assay | Homo sapiens | 6 | ALA5120760 | cell-based format | Scientific Literature | |
14. | ALA5121470 | Functional | Cytotoxicity against human A-431 cells assessed as inhibition of cell proliferation incubated for 5 days by MTT assay | Homo sapiens | 6 | ALA5120760 | cell-based format | Scientific Literature | |
15. | ALA5121471 | Functional | Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation incubated for 5 days by MTT assay | Homo sapiens | 6 | ALA5120760 | cell-based format | Scientific Literature |