| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4256221 | B | Inhibition of recombinant human full length ATR/ATRIP expressed in mammalian expression system using c-Myc-tagged p53 as substrate incubated for 15 mins followed by substrate addition measured after 25 to 35 mins by TR-FRET assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 2. | ALA4256222 | B | Inhibition of ATR in human HT29 cells assessed as reduction in Chk1 phosphorylation at Ser345 residues after 4 hrs by Alexa Fluor 488 staining based fluorescence assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 3. | ALA4256223 | B | Inhibition of ATR in human U2OS cells harboring ER-LBD fused TopBPI activation domain (978 to 1286 residues) assessed as reduction in 4-OHT-mediated nuclear translocation of TopBPI fragment by measuring gammaH2AX level after 24 hrs by Alexa Fluor 488 staining based fluorescence assay | Homo sapiens | 4 | cell-based format | Scientific Literature |
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