# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3615835 | B | Binding affinity to Mycobacterium tuberculosis H37Rv Biotin protein ligase expressed in Escherichia coli by ITC analysis | Mycobacterium tuberculosis H37Rv | 13 | assay format | Scientific Literature | ||
2. | ALA3615836 | B | Binding affinity to Mycobacterium tuberculosis H37Rv Biotin protein ligase expressed in Escherichia coli assessed as change in melting temperature measured across 10 to 85 degC with 1 min incubation per 0.5 degC increase by differential scanning fluorimetric analysis | Mycobacterium tuberculosis H37Rv | 13 | assay format | Scientific Literature | ||
3. | ALA3615837 | F | Antibacterial activity against Mycobacterium tuberculosis H37Rv measured at 10 to 14 days by broth microdilution method | Mycobacterium tuberculosis | 12 | organism-based format | Scientific Literature | ||
4. | ALA3615838 | A | Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA3615839 | A | Drug uptake in Mycobacterium tuberculosis H37Rv at 25 uM after 24 hrs by LC-MS/MS analysis | Mycobacterium tuberculosis H37Rv | 2 | organism-based format | Scientific Literature |